Explore our highly certified, factory-direct industrial ingredients optimized for pharmaceutical and supplemental applications.
Transitioning from traditional probiotics to clinically defined bio-active formulations.
Taxonomic Update Note: Formerly classified as Lactobacillus rhamnosus, the official scientific name has updated to Lacticaseibacillus rhamnosus following the 2020 taxonomic revision of the Lactobacillaceae family. Our laboratory and manufacturing processes strictly reflect this updated nomenclature to align with modern regulatory and scientific standards globally.
Lacticaseibacillus rhamnosus is a gram-positive, rod-shaped, heterofermentative facultative anaerobic bacterium. Due to its superior capacity to withstand acid and bile environments, it boasts unparalleled colonization rates within the mammalian gastrointestinal tract. Our highly standardized wholesale powder is formulated through sophisticated anaerobic fermentation and specialized stabilization parameters designed to maximize CFU (Colony-Forming Units) longevity during retail shelf life.
To ensure high efficacy, Shaanxi ShineHerb Biotech uses cutting-edge lyophilization (freeze-drying) technology combined with unique cryoprotectant formulations. This prevents cell wall degradation and ensures that the water activity ($a_w$) is consistently maintained below 0.1, preserving stability at room temperature.
| Parameters | Specifications Standard |
|---|---|
| Appearance | Off-White to Light Yellow Powder |
| Viable Cell Count | ≥ 1.0 × 1011 CFU/g (Customizable up to 5.0x1011) |
| Water Activity ($a_w$) | ≤ 0.10 |
| Loss on Drying | ≤ 5.0% |
| Heavy Metals (as Pb) | ≤ 1.0 ppm |
| Pathogenic Yeast & Molds | ≤ 50 CFU/g (Pathogens: Negative) |
Established in 2002, Shaanxi ShineHerb Biotech Co., Ltd. (located in the Hi-Tech Zone of Xi'an, Shaanxi Province, China) is a premier high-tech enterprise engaged in the intensive research, custom synthesis, and international export of Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates.
With over 20 years of dedication to biological raw materials, our manufacturing architecture features state-of-the-art biological fermentation workshops and Class-100,000 cleanroom environments to guarantee absolute sterility and consistency. We are highly trusted by buyers in over 50 countries, spanning Europe, North America, Latin America, and Southeast Asia.
Providing high-viability active strains to drive innovation in healthcare, cosmetics, and functional nutrition.
Optimized for encapsulation (hard-shell capsules, tablets) and dry-powder sachet formulas. Excellent thermal resistance ensures viability when mixed into complex nutritional supplement matrices.
Widely utilized in fermented milks, yogurts, plant-based dairy alternatives, and functional powders. Resistant to pasteurization heat limits and post-acidification deterioration.
Lacticaseibacillus rhamnosus lysates are increasingly used in topical cosmetic applications to strengthen skin barrier mechanisms, balance microbiome flora, and optimize sebum regulation.
Our commitment to pharmaceutical manufacturing protocols assures reliable industrial supply.
Quality represents the structural core of Shaanxi ShineHerb Biotech. We have established an exhaustive internal quality management system covering raw materials inspection, optimized fermentation temperature configurations, organic solvent monitoring, and modern analytical testing using HPLC, GC, and Atomic Absorption Spectrometry.
Our production pipelines operate under sterile GMP environments, conforming fully to FDA regulations, Kosher, and Halal specifications. We prioritize consistent strain verification via rRNA gene sequencing, verifying genetic stability across every produced batch.
SGS heavy metal and organic solvent clearance verified.
Free of yeast, molds, and industrial chemical contaminants.
From custom strain blending to finished-product contract manufacturing.
Create complex probiotic combinations blending Lacticaseibacillus Rhamnosus with prebiotics (Inulin, FOS), natural botanical extracts, or essential enzymes.
Equipped to manufacture high-purity Powders, Tablets, Hard Capsules, Softgels, Gummies, and dry Solid Beverages, complete with custom flavoring and dye options.
Complete regulatory-compliant packaging design, bottle labeling, moisture-controlled aluminum sealing, and outer cardboard boxing tailored to your regional regulations.
Our raw materials conform with the dynamic food-safety frameworks of regulatory authorities worldwide.
Good Manufacturing Practice ensures standard production processes.
U.S. Food & Drug Administration compliant facilities.
Guaranteed biological, chemical, and physical risk prevention.
Strict adherence to orthodox food purity guidelines.
Global standardized operating guidelines.
Independent laboratory purity and safety checks.
Muslim-friendly dietary safety and purity.
Probiotics represent live cultures susceptible to thermal inactivation. Shaanxi ShineHerb Biotech implements robust containment strategies to safeguard cell viability during transit.
Take an online tour of our facility and check our latest research and QC standards.
Key information regarding strain selection, storage protocols, and business-to-business logistics.
They refer to the exact same probiotic organism. In April 2020, a global consortium of microbiologists restructured the massive genus Lactobacillus due to its genetic diversity. The strain was officialized as Lacticaseibacillus rhamnosus. This update did not modify the genetic makeup or efficacy of the strain itself, but using the updated name is highly recommended to meet modern regulatory guidelines.
We combine advanced double-layer microencapsulation (using lipid-protein matrices) and specialized freeze-drying cryoprotectants (including trehalose). By reducing water activity below 0.1, we prevent metabolic activity from prematurely starting inside the powder, allowing our Lacticaseibacillus rhamnosus powder to maintain ≥80% viability at room temperature ($25^\circ\text{C}$) for up to 24 months in sealed original packaging.
Our standard MOQ for pure freeze-dried Lacticaseibacillus rhamnosus powder starts at 10 kg, which fits the standard requirements for R&D pilots and formulation scale-ups. However, we also offer custom sample volumes (e.g., 100g to 1kg) for rigorous lab and microbiological verification beforehand.
Yes. Every single batch of Lacticaseibacillus rhamnosus exported by Shaanxi ShineHerb Biotech Co., Ltd. is accompanied by a Certificate of Analysis (CoA) containing our HPLC test results, heavy metal limits, CFU validation counts, and water activity analysis. We also support external third-party analysis by SGS or Eurofins upon custom request.
Get in touch with Shaanxi ShineHerb Biotech's technical consulting team for instant price quotes, formulation compatibility tests, and complimentary lab-grade samples. Our specialized scientists are online 24/7 to design the perfect solutions for your brand.
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