Direct from Shaanxi ShineHerb Biotech Co., Ltd. - Standardized quality meeting USP, EP, and CP requirements.
A Comprehensive Industrial Whitepaper on Sourcing, Synthesis, and Clinical Grade Production for Global Procurement Managers.
Arecoline Hydrobromide (CAS 300-39-0) is the hydrobromide salt form of the alkaloid arecoline, naturally derived from the seeds of the betel nut palm, Areca catechu, or synthesized through high-yield organic chemical pathways. Chemically identified as methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate; hydrobromide, this molecule exhibits highly active parasympathomimetic properties, functioning as an agonist at muscarinic acetylcholine receptors (M1, M2, M3, and M4 subtypes).
For industrial applications, especially in pharmaceutical R&D and veterinary drug manufacturing, establishing a secure, standard-conforming supply chain is critical. The substance presents as a white crystalline powder, highly soluble in water and ethanol. Our manufacturing lines implement advanced crystallization controls to ensure uniform crystal habit, optimal bulk density, and zero residual solvents (aligned with ICH Q3C Guidelines).
| Parameter | Standard (USP / EP Reference) | ShineHerb Guaranteed Quality |
|---|---|---|
| CAS Number | 300-39-0 | Verified 300-39-0 |
| Assay (HPLC) | ≥ 98.0% | ≥ 99.5% (Typical Batch 99.8%) |
| Melting Point | 171 °C to 174 °C | 172 °C - 173.5 °C |
| Heavy Metals | ≤ 10 ppm | ≤ 5 ppm |
| Loss on Drying | ≤ 1.0% | ≤ 0.5% |
The supply chain for alkaloids such as Arecoline Hydrobromide has faced intense volatility due to shifting regulatory policies, agricultural variability of feedstock materials, and environmental audits in primary industrial manufacturing parks. Global buyers must transition away from intermediary brokers toward verified primary production factories.
Shaanxi ShineHerb Biotech Co., Ltd. resolves this industrial bottleneck by utilizing an integrated supply model. Through our advanced synthesis facilities in Shaanxi Province, we decouple production from agricultural limits. By starting from synthetic nicotinic acid pathways, our chemical processing yields consistent volumes regardless of seasonal harvests. This guarantees global research centers, veterinary labs, and formulation firms an uninterrupted supply route.
Arecoline Hydrobromide holds a unique therapeutic footprint. Sourcing teams typically represent three primary industries:
In accordance with Google's search quality guidelines and global E-E-A-T principles, we maintain documentation systems that guarantee raw material traceability. All batches are accompanied by a comprehensive Certificate of Analysis (COA), Fourier-transform Infrared Spectroscopy (FTIR) spectrum reports, and High-Performance Liquid Chromatography (HPLC) chromatograms.
Furthermore, our operations are ISO9001 and GMP-certified. We understand that importing high-purity alkaloids requires navigating complex local customs protocols. ShineHerb Biotech supplies all necessary safety sheets (SDS), non-dangerous chemical declarations, and customs-clearance documentation to ensure seamless regulatory transitions in European, North American, and Asian target ports.
A professional B2B pioneer in the extraction, synthesis, and export of high-grade active raw materials for over 20 years.
Our main products include Lactase, Bromelain, Pancreatin, Papain, Quercetin, NAC, PQQ, and Glucosamine Sulfate 2KCL, exported to over 50 countries.
Fully compliant with global pharmaceutical and food ingredient distribution standards:
Years of B2B Sourcing Experience
Countries Exported to Globally
Average Batch Chemical Purity
Dedicated Regulatory Support
Ensuring sustainable manufacturing, high product yield, and seamless cross-border shipping logistics.
Critical inspection of precursor agents. We use chromatographically certified intermediates to eliminate trace isomers and metal residues at the source.
The chemical reaction is monitored under real-time HPLC to guide esterification, preventing side-reactions and ensuring maximum yields of arecoline base.
Introduction of pharmaceutical-grade hydrobromic acid followed by precise temperature-drop recrystallization to yield pure, ultra-white crystalline salts.
Double-layered food-grade PE vacuum lining with protective aluminum outer drums prevents humidity absorption and degradation during trans-oceanic shipping.
Welcome to Shaanxi ShineHerb Biotech Co., Ltd., a professional enterprise engaged in the research, production, and exports of Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates. We are committed to providing global customers with competitive pricing, stable and reliable product quality, and professional, efficient services.
With over 20 years of experience in the raw materials industry, ShineHerb Biotech continues to strengthen its technical capabilities and improve product quality. Our main products include Lactase, Bromelain, Pancreatin, Papain, Quercetin, N-Acetyl-L-Cysteine (NAC), PQQ, and Glucosamine Sulfate 2KCL, among others. These ingredients are widely used in pharmaceuticals, dietary supplements, beverages, cosmetics, and food additives.
Quality is the core of a company’s survival and development. ShineHerb Biotech has established a strict quality management system, covering raw material inspection, production process control, solvent and excipient management, and final product testing, ensuring rigorous quality control at every stage. Products consistently meet USP, EP, and CP standards.







From formulation and design to production and packaging, we handle every step so you can focus on building your brand.
We provide hassle-free global shipping options via multi-channel logistics:
Watch our facility overview and product processing walkthrough:







Technical, regulatory, and sourcing answers for B2B procurement professionals sourcing Arecoline Hydrobromide.
High-quality extracts and botanical components manufactured under strict GMP controls.
Partner with Shaanxi ShineHerb Biotech Co., Ltd. for scalable APIs, botanical extracts, custom formulations, and global compliance support.
Corporate Headquarters: Hi-Tech Zone, Xi'an City, Shaanxi Province, China.
Support Center: 24/7 client portal for quick responses to all technical and bulk pricing inquiries.