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Arecoline Hydrobromide (CAS 300-68-5) is the hydrobromide salt of arecoline, a natural pyridine alkaloid found in the areca nut (Areca catechu). As a selective partial agonist of muscarinic acetylcholine receptors (specifically M1, M2, M3, and M4 subtypes), this substance has become an invaluable tool in biochemical research, veterinary parasitology, and pharmaceutical syntheses.
Due to its intense physiological properties, buying Arecoline Hydrobromide demands strict verification of manufacturing processes, raw material sources, and analytical profiles. Our facilities leverage state-of-the-art synthetic and isolation methodologies to output consistent API grade quality matching international pharmacological monographs.
| Characteristic | Specification Target |
|---|---|
| Purity (HPLC) | ≥ 98.0% / ≥ 99.0% |
| Appearance | White to off-white crystalline powder |
| Melting Point | 169 °C - 171 °C |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals | ≤ 10 ppm |
Analyzing B2B procurement patterns, regulatory parameters, and strategic sourcing variables.
Modern pharmaceutical manufacturers and academic research labs globally face increasingly complex compliance environments. The procurement of Arecoline Hydrobromide is heavily governed by local drug administrations, including FDA, EMA, and NMPA regulations, due to its cholinergic properties. Understanding these international compliance structures is vital for seamless import and export operations.
Global procurers prioritize companies that supply complete validation documentation. A standard shipment should include a batch-specific Certificate of Analysis (COA), Material Safety Data Sheets (MSDS) detailing chemical hazards, and documentation supporting compliance with Pharmacopoeia standards (USP, EP, or CP).
Arecoline Hydrobromide is a crystalline solid susceptible to moisture degradation. B2B buyers require specialized packaging (such as double-layered polyethylene bags sealed within fiber drums) and cold-chain or dark storage controls to prevent degradation during ocean or air transit.
As pharmaceutical pipelines expand, demands shift from laboratory pilot batches (grams) to high-volume industrial quantities (metric tons). Leading supply exporters must possess the capacity to scale synthesis lines smoothly without batch-to-batch chemical variance.
Established in 2002, Shaanxi ShineHerb Biotech Co., Ltd. (located in the Hi-Tech Zone of Xi'an, Shaanxi Province) has positioned itself as an industry leader in researching, manufacturing, and exporting biological raw materials. With over 20 years of experience, we specialize in high-purity APIs, natural plant extracts, enzyme preparations, vitamins, and specialized intermediates.
Through continuous innovation and technical upgrading, our high-precision synthesis and extraction lines produce ingredients that strictly meet international guidelines (USP, EP, CP). Currently, our distribution pathways stretch to over 50 countries across North America, Europe, and Asia-Pacific, ensuring robust supply chains for top-tier pharmaceutical and dietary supplement formulations.
How automation, IoT, and high-tech tracking maintain chemical purity and uninterrupted supply lines.
Inside our automated API production lines (View factory video tour)
Our manufacturing complex utilizes Industrial Internet of Things (IIoT) sensors to monitor heat, reaction pressure, and solvent flow rates in real time. For sensitive processes like the isolation and salt-conversion of Arecoline Hydrobromide, this system limits impurities to fractions well below national guidelines.
Furthermore, automated environmental chambers ensure that delicate powders do not absorb moisture during post-processing packaging. This strict integration of automation avoids human error and delivers batch consistency, lowering procurement risks for global buyers.
Our strategic partnerships with premium courier networks and global logistics ports enable rapid clearance and shipping. Through integrated air, sea, and rail channels (including major routes linking China to Central Asia and Europe), we maintain constant material delivery timelines despite shifting global geopolitical realities.
Where Arecoline Hydrobromide is deployed across sectors like medicine, neuroscience research, and veterinary fields.
Within laboratory settings, researchers employ Arecoline Hydrobromide to investigate central nervous system diseases, notably Alzheimer's disease and cognitive decline. Its agonist activity at muscarinic receptor sites aids in understanding memory retrieval, synaptic plasticity, and acetylcholine pathway dynamics.
In veterinary medicine, particularly across major agricultural areas (including Australia, South America, and Europe), arecoline compounds have been historically formulated as tapeworm therapeutics for livestock and canine species. It stimulates peristaltic movement of the gut, forcing parasite detachment.
With agriculture shifting away from toxic organophosphates, researchers are studying pyridine alkaloids like arecoline as natural templates for bio-rational pesticides. They target the nervous systems of targeted agricultural pests while boasting rapid soil biodegradation profiles.
Whether you require customized active ingredient concentrations, bespoke packaging formats, or private labeling, Shaanxi ShineHerb Biotech Co., Ltd. provides comprehensive OEM/ODM assistance. From powder processing to formulation, capsule filling, tableting, and custom labeling, our factory floor is equipped to execute projects of various scopes.
Our facilities are audited to meet international food, chemical, and pharmaceutical standards.
Good Manufacturing Practice standards for absolute batch consistency.
Internationally audited quality systems spanning our entire design-to-ship pipeline.
Valid registrations enabling smooth importation into United States markets.
Kosher, Halal, and HACCP certified options for diversified global demographics.
Exporting chemical components requires meticulous attention to international safety labels, regulatory compliance, and cross-border paperwork. Shaanxi ShineHerb Biotech Co., Ltd. provides multi-channel delivery configurations designed to match your lead-time expectations and regulatory demands.
Addressing key queries related to regulatory compliance, technical properties, and purchase parameters.
We primarily utilize High-Performance Liquid Chromatography (HPLC) coupled with ultraviolet detectors to determine assay purity. Additionally, we run Proton Nuclear Magnetic Resonance (1H-NMR) spectroscopy and gas chromatography (GC) to guarantee the absence of volatile organic solvents and residual reagents, confirming a minimum purity threshold of 98.0% or 99.0% based on customer requests.
Arecoline Hydrobromide is subject to distinct chemical classification rules depending on the destination jurisdiction. Shaanxi ShineHerb Biotech provides complete safety paperwork, including updated GHS-compliant Safety Data Sheets (SDS), certificates of origin, and custom HS codes. We strongly recommend that buyers check local import regulations regarding muscarinic receptor agonists prior to confirming orders.
Our MOQs are flexible, catering to different stages of development. We supply pilot run quantities beginning at 100g to 1kg for R&D laboratories, alongside high-volume production batches ranging from 25kg up to several metric tons. Contact our customer service team to request custom scale quotes.
To shield the hydrobromide salt from moisture absorption, we use vacuum-sealed, double-layer food-grade polyethylene interior bags packed inside heavy-duty, impact-resistant fiber drums. For moisture-sensitive or dangerous compounds, we also offer vacuum-flushed aluminum foil wrapping and include desiccants to ensure product integrity.
Yes, all chemical and biological batches are manufactured under strict protocols aligned with USP, EP, or CP guidelines. A corresponding Certificate of Analysis (COA) is issued for every batch, confirming compliance with standardized limits for impurities, ash, heavy metals, and physical-chemical constants.
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