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NMN (Beta-Nicotinamide Mononucleotide) is a substance naturally present in the human body and participates in the synthesis of NAD+ in cells. NAD+ is the most important coenzyme in the human body. It participates in thousands of biocatalytic reactions in the human body and is an essential substance for the human body. For example, metabolism, redox, DNA maintenance and repair, gene stability, epigenetic regulation, etc., all require the participation of NAD+.
NMN can be naturally synthesized in the human body and can also be derived from a variety of foods, including broccoli, cabbage, cucumber, edamame, avocado, etc., but the content is quite rare.
• NAD+ levels decrease rapidly with age: Nearly 50% reduction every 20 years. By 40, the NAD+ level in the human body is only 25% of that of a child.
• Dietary Limitations: Many natural foods contain NMN, but because the content is too low, it isn’t easy to rely on natural foods to supplement a sufficient amount of NMN. To consume 300mg of NMN, you need to eat about 54 pounds of broccoli and 32 pounds of edamame.
| Product name | CAS No. |
|---|---|
| NM Nicotinamide | 98-92-0 |
| NMN Nicotinamide mononucleotide | 1094-61-7 |
| NR Nicotinamide Riboside | 1341-23-7 |
| NRC Nicotinamide Riboside Chloride | 23111-00-4 |
| NAD+ Nicotinamide adenine dinucleotide | 53-84-9 |
| NADH Nicotinamide adenine dinucleotide, reduced coenzyme I | 606-68-8 |
| NADP Nicotinamide adenine dinucleotide phosphate | 53-59-8 |
| NMNH β-nicotinamide mononucleotide, reduced form, disodium salt | 108347-85-9 |
NMN bypasses the bottleneck of the NAMPT rate-limiting enzyme and can quickly replenish NAD+ in the body, making it an ideal supplement method. NMN can quickly enter the blood within 10 minutes, and after 30 minutes, it is absorbed by the body's organs and converted into NAD+.
Most oral NR is not converted into NMN but is instead digested into NAM, failing to bypass the restriction of the rate-limiting enzyme NAMPT in the salvage synthesis pathway, meaning its ability to supplement NAD+ is limited.
NAD+ is an important coenzyme in the mitochondria for aerobic oxidation and the metabolism of the tricarboxylic acid cycle to generate the energy molecule ATP. However, due to its large molecular weight, it is difficult for NAD+ to penetrate cell membranes directly, so it cannot be directly taken up.
Specializing in the production and sales of the Nicotinamide series. If you are interested in any of our products, please feel free to contact us at any time.
| Item | Specification | Result |
|---|---|---|
| Description | White powder | Conforms |
| Color | White | Conforms |
| Assay | ≥98% | 99.53%(HPLC) |
| Loss on drying % | ≤1% | 0.13% |
| PH value in water (100mg/ml) | 2.0~4.0 | 3.0 |
| Mesh size | 100% pass 80 mesh | Conforms |
| Lead (Pb) | ≤0.5 mg/Kg | Conforms |
| Arsenic (As) | ≤0.5 mg/Kg | Conforms |
| Mercury (Hg) | ≤0.5 mg/Kg | Conforms |
| Chromium (Cr) | ≤0.5 mg/Kg | Conforms |
| Ash Content % | ≤5.00% | 2.04% |
| Total Bacteria | ≤1000cfu/g | Conforms |
| Yeast & Mold | ≤100cfu/g | Conforms |
| Salmonella | Negative | Negative |
| E.Coli | Negative | Negative |
| Ethanol (GC) | ≤5000ppm | 100ppm |
| Weight | Packing method |
|---|---|
| 1kg | bag/kg, box outside (double plastic bag + Aluminum foil bag inside) |
| 10kgs, 25kg or more | by Drums or carton (2 layers plastic bag inside) |
| Weight | Delivery method | Delivery time | Destination |
|---|---|---|---|
| 1kg-25kgs | EMS, DHL, UPS, Fedex | 3-7 days | Door to door |
| 25kgs-100kgs | DHL, FedEx, by Air | 3-7 days | Door to door (to Airport by Air) |
| more than 100kgs | by Air | 3-7 days | Door to Airport |
| by Sea | 10-35 days | Door to port |
