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Sclareolide is a natural sesquiterpene lactone derived from Salvia sclarea L. (Clary Sage), widely recognized as the foundational building block for synthesizing high-value flavor and fragrance compounds, most notably Ambroxide (Ambroxan). In the wake of strict ESG regulations and the phaseout of animal-derived musk compounds, high-purity Sclareolide has transitioned from a specialty biochemical to a vital raw material.
Shaanxi ShineHerb Biotech leverages its 20+ years of botanical extraction expertise to supply global markets with premium Sclareolide, characterized by its outstanding crystal structure, virtual zero odor profile, and strict compliance with global chemical and food-grade standards.
With the cosmetics and fragrance industry steering clear of synthetic musk complexes due to toxicity and environmental persistence concerns, Sclareolide acts as the essential green pathway for producing high-grade Ambroxide, offering clean, natural stabilization properties.
Within functional dietary supplements, Sclareolide is highly regarded for its potential to stimulate cyclic adenosine monophosphate (cAMP) accumulation, boosting thermogenesis and lipolysis to aid clean fat oxidation without standard cardiac side effects.
Extensive research identifies Sclareolide as an effective plant-derived elicitor. It enhances systemic acquired resistance (SAR) in vegetable crops against fungal pathogens like powdery mildew, making it a valuable bio-pesticide component.
To facilitate formulation accuracy, Shaanxi ShineHerb Biotech operates precise quality control workflows. The following table showcases our primary technical specifications of Sclareolide.
| Parameter | Specification Requirement | Testing Methodology |
|---|---|---|
| Appearance | White to Off-White Crystalline Powder | Visual Inspection |
| Assay (Purity) | ≥ 98.0% | HPLC (High-Performance Liquid Chromatography) |
| Melting Point | 124.0°C to 127.0°C | Capillary Melting Point Method |
| Specific Rotation | -22.0° to -25.0° | Optical Polarimeter (c=1 in CHCl3) |
| Loss on Drying | ≤ 0.5% | Thermogravimetric Analysis |
| Heavy Metals (Pb, As, Hg, Cd) | ≤ 10 ppm total | ICP-MS (Inductively Coupled Plasma Mass Spectrometry) |
Traditionally, Sclareolide has been manufactured using hot solvent extraction of Salvia sclarea stalks, followed by multi-stage crystallization using hexane and ethanol. As standard environmental regulations tighten worldwide, chemical manufacturing demands low carbon footprints and zero toxic residue.
Shaanxi ShineHerb Biotech has pioneered a hybrid production route that significantly improves the extraction yield of sclareol from clary sage concrete before converting it into Sclareolide via oxidation. By transitioning to catalytic oxidation under mild temperature conditions, we avoid the heavy chromium reagents commonly used in legacy plants. This results in minimal solvent residues and an exceptionally clean crystallization process.
Ideal for luxury skincare brands based in the EU. High-purity Sclareolide serves as a stable brightening additive that is non-irritating, ensuring complete compatibility with EC No 1223/2009 standards.
Used as an active component in non-stimulant weight management capsules. Highly compatible with clean-label configurations, standard organic fillers, and gelatin-free softgels.
Optimized for large-scale conversion factories in China, India, and Japan. Consistently structured crystal shapes allow rapid biotransformation into high-value Ambroxan.
Established in 2002, Shaanxi ShineHerb Biotech Co., Ltd. is a professional enterprise engaged in the research, production, and exports of Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates. Headquartered in the Hi-Tech Zone of Xi'an, Shaanxi Province, we are committed to providing global customers with competitive pricing, stable and reliable product quality, and professional, efficient services.
Our quality management system spans raw material inspection, production process control, solvent and excipient management, and final product testing. With over 20 years of experience in the raw materials industry, ShineHerb Biotech continues to strengthen its technical capabilities and improve product quality.
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From formulation design to packaging, ShineHerb Biotech manages every stage of supplement production so you can focus on building your brand.
● Multiple Delivery Formats: Powders, Tablets, Hard Capsules, Softgels, Gummies, and Solid Beverages.
● Private Label Solutions: Custom packaging, specialized branding, and tailored ingredient concentrations.
● Compliance Engineering: Fully optimized to meet FDA, EFSA, and regional health authority frameworks.
Ensuring safe delivery to over 50 countries, Shaanxi ShineHerb Biotech implements robust containment protocols and temperature-stable shipping routes.
● Express Couriers: FedEx, DHL, UPS & EMS.
● Bulk Transport: Consolidated Air Cargo, Ocean freight, and international Railway shipping networks.
● Seamless Delivery: Specialized DDU (Delivered Duty Unpaid) and DDP (Delivered Duty Paid) channels to handle custom clearance with zero delay.
Find answers to technical and regulatory questions about Sclareolide procurement and formulation compatibility.
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