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Shikimic acid, chemically identified as (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-ene-1-carboxylic acid (CAS Number: 138-59-0), holds a pivotal position in organic synthesis, pharmacological development, and cosmetic formulations. As a central biochemical intermediate in the shikimate pathway of plants, bacteria, and fungi, it serves as the biosynthetical precursor for aromatic amino acids (phenylalanine, tyrosine, and tryptophan) and secondary metabolites, including lignins, flavonoids, and alkaloids.
From a global macro-supply chain perspective, Shikimic Acid acts as the essential chiral starting material for the synthesis of Oseltamivir Phosphate (Tamiflu), the foremost neuraminidase inhibitor utilized in the prevention and treatment of influenza strains (H1N1, H5N1, and seasonal flu mutations). The complexity of synthesizing this drug molecules synthetically makes natural extraction of Shikimic Acid from botanical sources, particularly Illicium verum (Star Anise), the primary, economically viable pathway for global pharmaceutical manufacture.
| Specification Parameter | Standard Value (USP / EP Grade) |
|---|---|
| Chemical Name | Shikimic Acid |
| CAS Registry Number | 138-59-0 |
| Molecular Formula | C7H10O5 |
| Molecular Weight | 174.15 g/mol |
| Purity (HPLC) | ≥98.0% - 99.5% |
| Appearance | Off-white to white crystalline powder |
| Heavy Metals | ≤10 ppm |
Analyzing the resource dominance, optimized extraction methods, and scale efficiencies of Chinese phytochemistry exporters.
Over 80% of the world’s Star Anise (Illicium verum) is cultivated in southwestern China, specifically in Shaanxi, Guangxi, and Yunnan provinces. This geographic concentration provides Chinese processors with unparalleled access to fresh harvests, eliminating the high logistics costs, storage degradation, and supply chain bottlenecks that affect non-domestic extractors. This proximity ensures price stability and a secure raw materials stream.
Modern Chinese extraction plants have moved beyond traditional aqueous boiling. Factories like Shaanxi ShineHerb Biotech utilize pressurized liquid extraction (PLE), green solvent crystallization, and industrial chromatography. These technologies yield a purity level exceeding 98.5% with minimal environmental impact. They also optimize yield ratios, lowering the per-kilogram cost for wholesale distributors worldwide.
Chinese biochemical manufacturers operate under stringent environmental and safety regulations. Production is aligned with Good Manufacturing Practices (GMP) and certified under ISO 9001:2015, HACCP, FDA, Halal, and Kosher protocols. This rigorous documentation ensures seamless clearance for customs, imports, and downstream processing in demanding pharmaceutical environments in the US and the EU.
While historically dominated by antiviral drug synthesis, the global demand for Shikimic Acid is shifting toward cosmetic applications. Researchers have highlighted its function as a natural exfoliating agent, offering a gentler alternative to alpha-hydroxy acids (AHAs) and beta-hydroxy acids (BHAs). Its structural properties make it an ideal choice for sensitive skin, assisting in acne control, tissue regeneration, and melanin inhibition without causing chemical irritation.
Furthermore, the agricultural sector uses Shikimic Acid derivative technologies as natural growth promoters and organic herbicides. This versatility makes it highly sought after by global procurement teams in pharmaceuticals, cosmetics, and agricultural biotechnology.
Welcome to Shaanxi ShineHerb Biotech Co., Ltd., a professional enterprise engaged in the research, production, and export of high-purity enzyme preparations, natural plant extracts, vitamins, amino acids, and pharmaceutical intermediates. Established in 2002, our company operates from the Hi-Tech Zone of Xi'an, Shaanxi Province, utilizing local rich botanical resources and modern manufacturing technologies.
With over 20 years of experience in the raw materials industry, we continue to strengthen our technical capabilities and improve product quality. Our main portfolio includes Lactase, Bromelain, Pancreatin, Papain, Quercetin, N-Acetyl-L-Cysteine (NAC), PQQ, and Glucosamine Sulfate 2KCL, alongside high-demand intermediates like Shikimic Acid. We are committed to providing global customers with competitive pricing, stable quality, and professional, efficient services.
At present, our products are exported to more than 50 countries and regions, including Europe, North America, and Southeast Asia, gaining wide recognition and trust from global purchasers.
Quality is the core of our survival. ShineHerb Biotech has established a strict quality management system covering raw material inspection, production process control, solvent residue testing, and final product release, ensuring compliance with USP, EP, and CP standards.
We provide full documentation (COA, MSDS, HPLC chromatograms, heavy metal profiles) and offer custom formulation, custom specifications, and tailored packaging to meet the specific research and manufacturing requirements of our partners.
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From raw botanical extract powders to customized product formulations, tablets, hard capsules, softgels, and functional gummies—ShineHerb Biotech delivers comprehensive contract manufacturing solutions.
We assist brands from formulation design to packaging selection. By utilizing our production lines, raw material sourcing, and quality management systems, you can reduce manufacturing overhead and accelerate your time-to-market.
Our raw material sourcing, extraction operations, and chemical processing facilities comply with rigorous international standards.
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Handling bulk chemical precursors and botanical extracts requires strict cargo safety measures, custom documentation, and temperature-controlled storage solutions. ShineHerb Biotech has established robust shipping routes to support various shipping modes:
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