Wholesale Acacetin Powder Suppliers & Exporters

Your Trusted Global B2B Partner for High-Purity Natural Actives, Contract Manufacturing, and Comprehensive Regulatory Compliance Support

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About Shaanxi ShineHerb Biotech Co., Ltd.

Welcome to learn about our company. Shaanxi ShineHerb Biotech Co., Ltd. is a leading high-tech professional enterprise specializing in the research, production, and global export of premium Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates. Headquartered in the state-level Hi-Tech Industrial Development Zone of Xi'an, Shaanxi Province, China, we have established ourselves as an industry benchmark for quality and supply consistency.

With over 20 years of robust experience in the biological and raw materials industry, ShineHerb Biotech continues to strengthen its technical capabilities and elevate product quality. Our core plant extraction portfolio features high-purity flavonoids, enzymes, and active nutrition components, including Lactase, Bromelain, Pancreatin, Papain, Quercetin, N-Acetyl-L-Cysteine (NAC), PQQ, and Glucosamine Sulfate 2KCL. These essential components are widely sought after across the pharmaceutical, dietary supplement, functional food and beverage, cosmetic, and livestock feed industries.

Currently, our distribution network encompasses more than 50 countries and regions including North America, Western Europe, and Southeast Asia. Built upon rigid quality standards, competitive pricing structures, and efficient customized services, we strive to establish long-term, mutually beneficial partnerships with global brands and distributors.

ShineHerb Biotech R&D Facility
2002 Established In
20+ Years Experience
50+ Exporting Countries
99% HPLC Purity Available

Acacetin Technical Profile & Macro-Industry Status

An in-depth scientific analysis of the extraction technology, market dynamics, and physiological properties of Acacetin (5,7-dihydroxy-4'-methoxyflavone).

Understanding Acacetin: Extraction, Synthesis & Specification

Acacetin is a natural O-methylated flavone chemical compound found in various botanical sources, most notably in Robinia pseudoacacia (Black Locust), Turnera diffusa (Damiana), and certain species of birch (Betula pendula). Structurally represented as 5,7-dihydroxy-4'-methoxyflavone, it possesses distinct pharmacological properties. Unlike crude plant extracts, high-purity Acacetin powder is highly valued in pharmaceutical research and premium health supplement formulations.

ShineHerb Biotech produces Acacetin powder through dual-method pathways: ultra-precise botanical extraction utilizing advanced chromatographic separation and high-purity chemical synthesis. Both lines yield standardized powders from 98% to 99% HPLC purity. Our botanical route leverages clean solvent technology and multiple macroporous resin stages to isolate the flavone while removing all pesticide residues, heavy metals, and natural contaminants, meeting strict EU and US regulations.

Key Technical Parameters & Product Specifications

Our industrial batch manufacturing runs are optimized for the following analytical standards:

Analytical Indicator Standard Specification (HPLC 98% Grade) Testing Methods
Appearance Light yellow to off-white crystalline fine powder Visual Inspection
Active Content (Acacetin) ≥ 98.0% (anhydrous basis) HPLC (High-Performance Liquid Chromatography)
Loss on Drying ≤ 2.0% USP <731> Oven Method
Heavy Metals (Pb, Cd, As, Hg) ≤ 10 ppm total (Pb ≤ 2ppm, As ≤ 1ppm) ICP-MS (Inductively Coupled Plasma Mass Spectrometry)
Residual Solvents Meets USP <467> and European Pharmacopoeia standards GC-MS (Gas Chromatography)
Microbiological Profile Total Plate Count ≤ 1000 cfu/g; Yeast & Mold ≤ 100 cfu/g USP <61> & <62> microbial limits testing

Pharmacological Mechanisms & Global Market Demand

The global demand for Acacetin powder is primarily driven by three core pharmacological behaviors:

  • Aromatase Inhibition: Acacetin acts as a natural selective aromatase inhibitor. By blocking the CYP19A1 enzyme pathway, it prevents the conversion of testosterone into estradiol. This makes it a popular active ingredient in male health supplements, athletic performance formulas, and post-cycle therapy (PCT) applications.
  • Anti-inflammatory and Cytoprotective Pathways: In-vitro and in-vivo research suggests Acacetin exerts strong anti-inflammatory effects by suppressing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) via the downregulation of NF-κB signaling pathways. It also displays cardioprotective, neuroprotective, and anti-osteoporotic potential.
  • Cosmetic Tyrosinase Inhibition: In skincare formulations, Acacetin has been studied for its ability to reduce melanin synthesis through the down-regulation of microphthalmia-associated transcription factor (MITF) and subsequent tyrosinase inhibition. It helps control hyperpigmentation and protects dermal layers against UV-induced photo-damage.

North America and Western Europe represent the largest markets for pure Acacetin. Consumers in these regions are increasingly seeking clean-label, plant-derived alternatives to synthetic aromatase inhibitors and chemical anti-aging agents. In the Asia-Pacific region, the booming health wellness sector and cosmetic industry are driving local demand, paving the way for high-quality bulk supplies.

Macro-Industry Solutions & Contract Manufacturing

ShineHerb Biotech bridges the gap between raw botanical science and market-ready products with our extensive contract manufacturing capabilities.

Dietary Supplement Brands

We provide standard bulk Acacetin powder and design custom compound pre-mixes combining synergistic plant extracts (such as Diosmetin, Osthole, and Quercetin) for maximum biological efficacy.

Cosmeceuticals & Skincare

For cosmetic formulations, we customize particle size distributions (micronized powders) to enhance transdermal absorption. We also offer consulting on liposomal delivery systems for hydrophobic flavonoids.

Pharma & Research Centers

We supply analytical-grade reference standards, high-purity synthesis intermediates, and detailed documentation packs including NMR, HPLC chromatograms, and heavy metal profiling reports.

Supplement Custom Manufacturing Flow

Custom Supplement Manufacturing (OEM / ODM)

ShineHerb Biotech offers full-format OEM and ODM manufacturing services to bring your brand to market quickly. We manage the process from ingredient sourcing and custom formulation to tableting, encapsulating, and packaging.

  • Multiple Formats: Bulk fine powders, custom tablets, hard capsules (gelatin & veggie), softgels, chewable gummies, and solid dry beverages.
  • Customized Formulation: Modify dissolution rates, mask botanical tastes with natural sweeteners (like D-Allulose), and combine targeted vitamins and amino acids.
  • Private Label Support: Tailored packaging configurations (bottles, jars, sachets) with compliant nutritional labeling for US, EU, and international target markets.
  • Low MOQ Trial Runs: Test the market viability of new formulas with small-scale production trials before scaling up.

Uncompromising Quality Assurance & GMP Standards

Our quality-first philosophy is backed by rigorous testing systems, cutting-edge analytics, and international certifications.

GMP Compliance & Documentation

Our production facilities operate strictly under Good Manufacturing Practice guidelines. Every batch of Acacetin powder is issued a detailed Certificate of Analysis (COA), Allergen Statements, Non-GMO declarations, and MSDS sheets.

Advanced In-House Analytical Testing

Our QA/QC laboratories utilize advanced instruments, including High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), ICP-MS, and UV spectrophotometers, to confirm purity, detect residue, and verify consistency.

Traceable Supply Chain

From initial plant collection in partner forests to final crystallization and packaging, every stage is recorded in our ERP system, ensuring total safety and batch-to-batch traceability.

Laboratory Quality Control Extraction Tanks Purification Line GMP Clean Room
Production Facility 2 Drying Area Warehouse Storage Packaging Area
Quality Control Instruments Logistics Center

State-of-the-Art Facilities

Our manufacturing equipment is updated annually to incorporate the latest green chemistry technology, reducing environmental impact and improving yield quality.

Accredited Certifications

ShineHerb Biotech complies with global food and drug safety standards. Our production processes are verified by international testing agencies.

HACCP

HACCP

Guaranteed Food Safety Management

GMP

GMP

Good Manufacturing Practice Standards

Kosher

Kosher

High-Quality Certified Ingredients

ISO

ISO

ISO9001 International Quality Management

FDA

FDA

U.S. FDA Compliance Facility Registration

SGS

SGS

Rigorous Chemical & Heavy Metal Testing

HALAL

HALAL

Halal Certified for Muslim Consumers

Quality Certificates Gallery

Inspect our certified reports, validation documents, and laboratory analysis slides.

Certificate 1 Certificate 2 Certificate 3 Certificate 4
Certificate 5 Certificate 6 Certificate 7

Hassle-Free Global Logistics & Support

ShineHerb Biotech has developed a secure multi-channel shipping network to provide seamless delivery of botanical raw materials and finished products to overseas facilities.

  • Flexible Express Options: Partnered with FedEx, DHL, UPS, and EMS for fast-transit door-to-door delivery of small trial orders and chemical standard references.
  • High-Volume Sea & Air Freight: We coordinate directly with global port authorities for full container load (FCL) and less than container load (LCL) shipments.
  • Railway Transport Networks: Access to the China-Europe Railway Express route, offering cost-effective overland transport across Central Asia and continental Europe.
  • DDU & DDP Services: We handle complete import customs clearances, duty payments, and local tax declarations in key markets, reducing clearance delays.
Global logistics distribution network

Technical Roadmap & Future Outlook

Where plant extract science meets high-tech biotechnology. Explore the upcoming innovations in the production and application of Acacetin.

Sustainable Biosynthesis of Flavonoids

While traditional solvent extraction and pure chemical synthesis remain industry mainstays, ShineHerb Biotech is investing in enzymatic biosynthesis and microbial cell factory engineering (using Saccharomyces cerevisiae). Biosynthesis provides a zero-carbon, green chemistry path that yields highly pure Acacetin without agricultural variable costs, matching the strict raw material standards of the global skincare and health industries.

Bioavailability Enhancement (Nano-Carrier Systems)

Flavonoids like Acacetin are naturally limited by low water solubility and fast metabolism in the gut. Our research team is developing liposomal dispersion technologies and micro-encapsulations using food-grade Cyclodextrin complexes. These modifications increase the active absorption rate in nutritional supplements and cosmetic topical serums, helping brands improve formulation efficacy.

Company & Production Video Walkthrough

Take a virtual tour of Shaanxi ShineHerb Biotech's manufacturing floor, clean extraction lines, and packaging processes.

Company Tour & Facilities Video

Active Ingredient Production Process

Frequently Asked Questions & Support

Find answers to common questions about product purity, minimum order quantities, regulatory compliance, and customized OEM options.

What is the standard purity of your wholesale Acacetin powder, and how is it verified?
Our standard commercial batch of Acacetin powder has a purity of ≥98% and ≥99%, verified by High-Performance Liquid Chromatography (HPLC). We analyze chemical identity via nuclear magnetic resonance (NMR) spectroscopy and inspect heavy metals and solvent residues via ICP-MS and Gas Chromatography (GC-MS).
Do you support custom formulations combining Acacetin with other plant extracts?
Yes. We offer contract manufacturing and customized formulation services. We can blend Acacetin with other active compounds from our portfolio—such as Resveratrol, Osthole, Diosmetin, or Quercetin—to meet your specific formulation requirements.
What is the minimum order quantity (MOQ) for bulk purchases?
For standard bulk raw materials, our minimum order starts at 1 kg. For custom formulas, private label tablets, capsules, or gummies, MOQs vary depending on the production requirements. Contact our B2B sales team for a custom quote.
What regulatory support do you provide for importing into the United States and European Union?
We provide comprehensive documentation, including Third-Party Analytical Reports, Allergen declarations, Non-GMO declarations, and safety datasheets (MSDS/SDS). Our products meet USP, EP, and CP standards, and we can assist with FDA registry compliance and EU Novel Food dossiers.
How do you guarantee batch-to-batch stability and control impurities?
Our quality management system tracks all parameters, including crystallization temperature, reaction times, solvent purity, and packaging conditions. Retention samples from every batch are stored in our QC archive for 2 years for comparison and tracing.

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