Explore our top raw materials verified by HPLC & ISO standards for global export.
Oxy-resveratrol (trans-2,3',4,5'-tetrahydroxystilbene) is a naturally occurring polyphenol structural analogue of resveratrol. Primarily extracted from the heartwood of Artocarpus lakoocha or the root bark of Morus alba (White Mulberry), it has emerged as a gold-standard active ingredient in global skin biology, cosmetic formulations, and nutritional supplements. Over the past decade, the global cosmetic ingredient market has transitioned from synthetic pigment reducers (such as hydroquinone) to bio-based alternatives due to strict safety regulations in Europe and North America.
Recent semantic search trends reveal that R&D formulation specialists are actively seeking natural compounds that demonstrate superior tyrosinase inhibition. Biochemically, Oxy-Resveratrol shows an exceptional ability to bind with the active site of tyrosinase, the rate-limiting enzyme in melanogenesis. This competitive and non-competitive mixed inhibition mechanism effectively prevents the oxidation of L-DOPA, leading to powerful anti-hyperpigmentation and anti-photoaging outcomes.
Furthermore, as anti-aging therapeutics focus increasingly on cellular senolytics and mitochondrial health, dietary supplement brands are investigating bulk Oxy-Resveratrol for its high oral bioavailability compared to standard resveratrol. Its additional hydroxyl group increases water solubility, enhancing cellular uptake and antioxidant potential.
An analytical breakdown of chemical characteristics, bio-efficacy, and formulation parameters.
| Parameter | Oxy-Resveratrol (Tetrahydroxystilbene) | Standard Resveratrol | Formulation Impact / Advantages |
|---|---|---|---|
| Chemical Structure | C14H12O4 (4 hydroxyl groups) | C14H12O3 (3 hydroxyl groups) | Extra -OH group enhances water solubility & free radical scavenging kinetics. |
| Tyrosinase Inhibition Potency | IC50 ≈ 1.2 μM (Up to 150x stronger) | IC50 ≈ 180 μM | Oxy-Resveratrol delivers superior skin-brightening at significantly lower inclusion levels. |
| Water Solubility | Moderate to High (relative to stilbenes) | Extremely Low (insoluble in water) | Easier incorporation into aqueous cosmetic serums & liquid oral formulations. |
| Primary Bio-Activities | Tyrosinase inhibition, ROS scavenging, neuroprotection, anti-neuroinflammatory | Sirt1 activation, cardiovascular health, caloric restriction mimetic | Distinct positioning targeting both age-spot correction and cellular longevity. |
| Stability Profile | Sensitive to light/oxygen; requires carrier stabilization (liposomes/microcapsules) | Relatively stable in solid powder state | ShineHerb offers proprietary lipid-microencapsulated grades for optimized stability. |
Procuring raw materials like bulk Oxy-Resveratrol requires thorough risk assessment. Global purchasers from cosmetic conglomerates and nutraceutical manufacturers face persistent challenges: batch-to-batch consistency, heavy metal contamination (specifically lead and arsenic), pesticide residues, solvent residues (such as ethyl acetate or methanol), and microbiological counts.
At Shaanxi ShineHerb Biotech Co., Ltd., we address these regulatory demands by implementing strict quality control systems. Our extraction facility complies with GMP standards, and each production batch undergoes complete chromatographic profiling (HPLC, UV, and GC-MS). We ensure our clients receive a Certificate of Analysis (COA) for every shipment, detailing assay purity (98%+), heavy metal thresholds (<10ppm), and residue analysis conforming to USP <561> and European Pharmacopoeia (EP) requirements.
To support global supply chains, we offer tailored logistics options (DDP, DDU, FOB, CIF) via air, sea, and rail, facilitating smooth customs clearance in North America, Europe, and the APAC region.
How our advanced manufacturing framework optimizes cost and guarantees reliable production volumes.
Our facility utilizes automated, closed-loop extraction units to maximize active ingredient yields from Morus alba root bark while minimizing volatile solvent consumption.
We verify every batch of Oxy-Resveratrol. Our standard raw powder achieves 98%+ purity via HPLC, eliminating unwanted colored impurities to ensure the final product remains stable.
Utilizing low-temperature vacuum drying, we preserve the molecular integrity of heat-sensitive stilbenoids, preventing oxidative degradation during final processing stages.
Technical guidelines for formulating with Oxy-Resveratrol across multiple industries.
Used at concentration levels of 0.5% - 2.0% in skincare creams and serums. Formulators should use stabilizing agents (such as ferulic acid, vitamin E, or cyclodextrin encapsulation) to maintain biological activity and prevent color shifts in water-based formulas.
Formulated into capsules and tablets as a bioavailable alternative to resveratrol. Commonly combined with Coenzyme Q10, NMN, or Quercetin to leverage synergistic pathways targeting cell longevity and cardiovascular health.
Oxy-resveratrol helps neutralize free radicals generated by UVA and UVB exposure. Incorporating it into post-sun recovery lotions reduces erythema and downregulates the intracellular inflammatory cascade.
Welcome to Shaanxi ShineHerb Biotech Co., Ltd., a professional enterprise engaged in the research, production, and export of Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates. We are committed to providing global customers with competitive pricing, stable and reliable product quality, and professional, efficient services.
With over 20 years of experience in the raw materials industry, ShineHerb Biotech continues to strengthen its technical capabilities and improve product quality. Our main products include Lactase, Bromelain, Pancreatin, Papain, Quercetin, N-Acetyl-L-Cysteine (NAC), PQQ, and Glucosamine Sulfate 2KCL, among others. These ingredients are widely used in pharmaceuticals, dietary supplements, beverages, cosmetics, and food additives.
At present, our products are exported to more than 50 countries and regions, including Europe, North America, and Southeast Asia, and have gained wide recognition and trust from customers worldwide. Established in 2002 in Hi-Tech Zone Xi'an, Shaanxi Province, we continue to prioritize quality as the foundation and customer needs as the driving force.
From raw powder processing to complete finished goods, ShineHerb Biotech provides customized formulation development, dose design, and packaging services for private labels worldwide.
Our manufacturing processes are audited and certified by global standards to guarantee product safety and regulatory compliance.
Take a virtual tour of our extraction facility and laboratory.
Key technical and regulatory answers for formulation scientists, research groups, and procurement managers.
Supplement and cosmetic raw materials for global procurement. Click below for detailed specifications.
Key raw materials from our Xi'an processing facility, available for immediate shipping.
Exporting raw active ingredients globally requires dependable logistics partners. ShineHerb Biotech maintains a robust logistics network to ensure your orders arrive securely and on schedule, regardless of destination country or shipping volume.
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