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Natural Gentiopicrin (CAS No. 20831-76-9) is a characteristic secoiridoid glycoside compound found primarily in plants belonging to the Gentianaceae family, particularly in Gentiana lutea (Yellow Gentian) and Gentiana scabra. Historically valued in traditional medicine, Gentiopicrin has emerged as a premium bioactive target molecule in modern pharmaceuticals, dietary supplements, and specialized skin-repair cosmetic formulations.
As leading Gentiopicrin manufacturers and global exporters, we utilize advanced isolation methods to secure highly refined extracts with standardized concentrations ranging from 10% up to 98% HPLC purity. Our extraction protocol preserves the stereochemical configuration of the compound, ensuring optimal physiological activity when formulated.
Research confirms that Gentiopicrin exhibits powerful pharmacological benefits:
Global demand for standardized phytochemicals like Gentiopicrin has grown due to the shift toward natural remedies and preventative healthcare. Because it is highly soluble in water and ethanol, formulators can easily integrate it into functional beverages, oral drops, hard capsules, tablets, and topical cosmetics.
Detailed technical parameters for bulk raw materials procurement:
| Parameters | Specifications Standard |
|---|---|
| Active Compound | Gentiopicrin (Secoiridoid Glycoside) |
| CAS Registry Number | 20831-76-9 |
| Extract Sources | Gentiana scabra Bunge / Gentiana lutea Root |
| Purity Grades Available | 10% - 98% (HPLC) |
| Appearance Profile | Light yellow to white crystalline powder |
| Loss on Drying | ≤ 5.0% |
| Heavy Metals (As Pb) | ≤ 10 ppm |
| Solvent Residues | Meet USP/EP standards (Ethanol-only extraction) |
Strategic insights for raw material buyers, sourcing directors, and product development managers.
Global pharmaceutical and nutraceutical buyers face common sourcing challenges, including variable assay percentages and poor quality control from uncertified brokers. Sourcing directly from an established manufacturer with over 20 years of experience, such as Shaanxi ShineHerb Biotech Co., Ltd., mitigates these supply chain risks.
In addition to strict raw material verification, professional buyers need customized solutions. For instance, the veterinary health sector uses low-grade Gentiopicrin for digestive stimulation, whereas the cosmetic industry requires >98% pure, decolorized Gentiopicrin to prevent formulation staining. By matching purification techniques with customer applications, we ensure cost-efficient procurement without compromising performance.
As the market moves toward clean-label and solvent-free ingredients, our production processes utilize environmentally friendly extraction technologies. By using water and grain-fermented ethanol instead of chlorinated hydrocarbons, we ensure that our extracts meet global health guidelines.
Welcome to Shaanxi ShineHerb Biotech Co., Ltd., a professional enterprise engaged in the research, production, and export of high-grade Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates. We are committed to providing global customers with competitive pricing, stable and reliable product quality, and professional, efficient services.
With over 20 years of experience in the raw materials industry, ShineHerb Biotech continues to strengthen its technical capabilities and improve product quality. Our main products include Lactase, Bromelain, Pancreatin, Papain, Quercetin, N-Acetyl-L-Cysteine (NAC), PQQ, and Glucosamine Sulfate 2KCL, among others. These ingredients are widely used in pharmaceuticals, dietary supplements, beverages, cosmetics, and food additives.
At present, our products are exported to more than 50 countries and regions, including Europe, North America, and Southeast Asia, and have gained wide recognition and trust from customers worldwide.
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Why leading global enterprises partner with ShineHerb Biotech for long-term ingredient supplies.
Quality is the core of our survival and development. ShineHerb Biotech has established a strict quality management system, covering raw material inspection, production process control, solvent and excipient management, and final product testing, ensuring rigorous quality control at every stage.
With over 20 years of experience in the raw materials industry, we assist client formulators with stability assessments, solubility optimization, and tailored ingredient solutions designed for regulatory approval.
Our manufacturing and processing adhere strictly to Good Manufacturing Practices (GMP) and ISO requirements, enabling smooth market registration and custom clearances in the USA, EU, and Asian markets.
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Meeting regulatory standards is essential. Shaanxi ShineHerb Biotech maintains a robust compliance framework verified by leading international agencies.
Guaranteed Food Safety Management & Risk Control
Good Manufacturing Practice Standard compliance
High-Quality Kosher Certification for Global Dietary Needs
Global Standard Recognition & International Industry Compliance
U.S. Food & Drug Administration Regulatory Compliance
Rigorous Quality Control Verified by a Global Verification Leader
Suitable for Muslim Consumers - Pure & Clean Certification
Beyond bulk raw material supplying, ShineHerb Biotech offers comprehensive contract manufacturing services. We can convert Gentiopicrin and other premium active ingredients into customer-ready dosage formats designed for retail markets.
Our turnkey contract manufacturing supports your brand from inception to launch: customized formulations, regulatory compliance, private label graphics, and final shipping logistics.
Delivering botanical extracts and active substances to over 50 countries requires strict logistical management. At Shaanxi ShineHerb Biotech Co., Ltd., we combine temperature-controlled packaging, reliable moisture barriers, and standard industrial containers to protect cargo during transit.
We provide full documentation for every export shipment, including:
Whether you require DDP delivery to your domestic warehouse or standard FOB port delivery, our logistics team simplifies the procurement process.
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Innovative extraction technologies driving increased biological availability and purer outputs.
Industrial chromatography has advanced the isolation of high-purity Gentiopicrin. While classic precipitation methods yield extracts with significant amounts of secondary glycosides and bitter compounds, our facility implements industrial-scale preparative HPLC systems. This allows us to offer 98% crystalline Gentiopicrin, minimizing trace contaminants for pharmaceutical applications.
To reduce dependence on wild-harvested *Gentiana* species, we are expanding our agricultural partnerships. By implementing good agricultural practices (GAP) at our cultivation locations, we control soil conditions, irrigation, and harvest timing to optimize natural Gentiopicrin levels in the roots.
Scientific research is exploring Gentiopicrin's potential benefits for metabolic health, inflammatory bowel issues, and cellular preservation. Our research group collaborates with academic institutes to explore liposomal delivery systems designed to enhance the bioavailability of this active compound in functional foods.
Below is a brief technical comparison of current extraction routes used in our facility:
| Method | Extraction Yield | Selectivity Profile | Environmental Footprint |
|---|---|---|---|
| Warm Ethanol Maceration | Medium-High | Broad Extract Profile | Moderate |
| Supercritical Fluid Extraction (CO2) | High | Excellent Selection | Very Low (Eco-Friendly) |
| Ultrasonic-Assisted Extraction | High | Excellent Target Preservation | Low |
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Looking ahead, ShineHerb Biotech will continue to adhere to quality as the foundation and customer needs as the driving force, continuously improving product quality and service standards. We place great importance on building long-term and stable partnerships with our customers, and are committed to providing global clients with reliable product quality and professional services.
Contact our technical sales team for specifications, pricing, and document packages. Let us help you select the ideal Gentiopicrin specification for your formulation.
Shaanxi ShineHerb Biotech Co., Ltd. - Hi-Tech Zone Xi'an, Shaanxi Province, China.
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