Direct supply from GMP-compliant manufacturing facilities with globally-recognized certification standards.
Proanthocyanidins, also known as condensed tannins, are a class of polymeric polyphenols that function as potent antioxidants. Primarily extracted from botanical sources such as grape seed, pine bark, and cranberry, these compounds possess unique structural varieties. Oligomeric Proanthocyanidins (OPCs), consisting of dimers, trimers, and tetramers, exhibit excellent bioavailability and rapid absorption in biological systems. On the other hand, Polymeric Proanthocyanidins (PPCs) feature higher polymerization levels and function effectively as gastrointestinal antioxidants and topical agents.
As a leading supplier, Shaanxi ShineHerb Biotech Co., Ltd. implements advanced membrane separation and clean solvent extraction technologies to selectively isolate specific polymerization states. This controls the balance of monomeric catechins, epicatechins, and oligomeric combinations, allowing us to supply highly bioactive raw materials that meet strict pharmaceutical and dietary supplement specifications.
Proanthocyanidins differ in efficacy and formulation performance depending on their plant origin. Here is the comparative roadmap of the major commercial varieties manufactured at our factory.
| Botanical Source | Common Standard Specifications | Primary Monomer Compounds | Main Applications | Extraction Technology Applied |
|---|---|---|---|---|
| Grape Seed Extract (Vitis vinifera) | OPC ≥ 95% (UV), Oligomers ≥ 60% (HPLC) | Catechin, Epicatechin, Gallic Acid | Cardiovascular Support, Skin Brightening, Anti-aging | Aqueous ethanol extraction + Column chromatography purification |
| Pine Bark Extract (Pinus pinaster) | Proanthocyanidins ≥ 95% (UV / HPLC) | Taxifolin, Procyanidin B1 & B2 | Cognitive health, Microcirculation, Anti-inflammatory | Subcritical low-temperature aqueous extraction |
| Cranberry Extract (Vaccinium macrocarpon) | PACs ≥ 15% - 50% (DMAC / UV) | A-type Proanthocyanidins (PAC-A) | Urinary tract health, Antibacterial coatings | Supercritical CO2 extraction combined with membrane filtration |
| Apple Extract (Malus domestica) | Polyphenols ≥ 80%, OPCs ≥ 40% | Phloridzin, Procyanidin B2 | Weight management, Metabolic regulation, Hair growth | Multi-stage vacuum concentration and freeze-drying |
Years of Raw Material Export Experience
Countries and Regions Exported to
High Purity Extraction Standards
USP, EP, & CP Compliance Guaranteed
Why multinational corporations select Shaanxi ShineHerb Biotech Co., Ltd. as their long-term supply partner.
Located in the Qinling Mountains area (Shaanxi Province), we have direct access to abundant, sustainably harvested botanical raw materials, ensuring continuous raw material availability even during seasonal shifts.
Our facility runs continuous counter-current extraction units, large-scale column chromatography networks, and spray dryers that produce up to 500 metric tons of standardized botanical powders annually, ensuring lower unit costs and high consistency.
Integrated logistics routes link Xi'an directly to major ports including Shanghai, Qingdao, and Shenzhen. Through our global shipping channels, we manage air, sea, rail, and express delivery, handling customs procedures with minimal delay.
At Shaanxi ShineHerb Biotech Co., Ltd., quality is the fundamental core of our operation. Our manufacturing systems enforce trace-back controls spanning botanical source cultivation, solvent and excipient parameters, purification configurations, and cleanroom packaging.
By complying with USP, EP, and CP standards, we monitor analytical parameters like heavy metals (arsenic, lead, mercury, cadmium), residual organic solvents, pesticide residues, and microbial contamination levels to ensure our ingredients are safe and stable for your formulations.
Create custom formulations containing standardized Proanthocyanidins, enzymes, plant extracts, vitamins, and minerals. We handle the manufacturing process so you can focus on building your brand identity.
Our ingredients hold certifications from respected international bodies, ensuring smooth custom clearance and formulation validation.
Guaranteed Food Safety Management
Good Manufacturing Practice System
Dietary Compliance Approved
International Standard Systems
U.S. Market Registry Compliant
Rigorous Physical & Chemical Verification
Certified for Muslim Consumers
Batch Traceability Documentation
A closer look at our extraction chambers, sterile packaging rooms, and rapid distribution operations.








The applications for Proanthocyanidins are growing rapidly. In the European Union and North America, dietary supplements containing OPCs are increasingly formulated with co-factors like Vitamin C, Quercetin, and Bromelain to improve cardiovascular benefits and boost cellular health.
In the cosmetics industry, microencapsulation technology is applied to stabilize proanthocyanidins, protecting them from oxidation and discoloration in aqueous solutions. This stabilization method is essential for skincare formulations like creams, anti-aging serums, and hyperpigmentation correctors.
At ShineHerb Biotech, we are developing a pipeline of water-soluble pine bark and grape seed extracts. These are designed to exhibit excellent clarity when dissolved, resolving the turbidity challenges common in RTD (Ready-To-Drink) functional beverages.
1. Nutricosmetics: Synergistic blend with Ascorbyl Glucoside and L-Carnosine for targeted melanin inhibition.
2. Cardiovascular Supplements: Combining grape seed extracts with Coenzyme Q10 for blood pressure regulation.
3. Active Packaging Films: Utilizing cranberry proanthocyanidins' antibacterial properties to create active food coatings.
4. Sport Nutrition: Formulations that help reduce oxidative stress and speed up recovery times.
Technical details, compliance protocols, and logistics information for global procurement managers.
A: UV-Vis measurement provides a total evaluation of polyphenolic content but can overstate purity by cross-reacting with other monomeric polyphenols. HPLC identifies specific oligomer units, while the DMAC method is the industry standard for A-type Proanthocyanidins from cranberries. We supply COAs with data from both methodologies to match your requirements.
A: For standard specifications, our MOQ starts at 1 kg for trial runs, with typical commercial orders shipping in 25 kg fiber drums. Lead times for stock items range from 3 to 5 business days. Custom formulations or specific particle sizes (like micronized powders) generally require 10 to 15 business days.
A: We use food-grade water and ethanol as extraction solvents. Any residues are removed during vacuum evaporation and spray-drying. Our finished products undergo testing to ensure residual solvent levels are well within USP and EP limits, with detailed documentation provided in each COA.
A: Yes, we provide comprehensive logistics solutions, including air, sea, and rail freight, along with DDU and DDP shipping. Our team manages import clearance, duties, and local delivery to your warehouse, ensuring a smooth, hassle-free logistics process.
A broad range of high-purity biological enzymes, organic minerals, and active cosmetic peptides.
Shaanxi ShineHerb Biotech Co., Ltd. is a professional enterprise engaged in the research, production, and exports of Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates. We are committed to providing global customers with competitive pricing, stable and reliable product quality, and professional, efficient services.
With over 20 years of experience in the raw materials industry, ShineHerb Biotech continues to strengthen its technical capabilities and improve product quality. Our main products include Lactase, Bromelain, Pancreatin, Papain, Quercetin, N-Acetyl-L-Cysteine (NAC), PQQ, and Glucosamine Sulfate 2KCL, among others. These ingredients are widely used in pharmaceuticals, dietary supplements, beverages, cosmetics, and food additives.
At present, our products are exported to more than 50 countries and regions, including Europe, North America, and Southeast Asia, and have gained wide recognition and trust from customers worldwide.
Enzymes: Stable enzyme activity, Customizable Specifications. Food Grade, Feed Grade, Pharma Grade, Cosmetic Grade. Global Certifications (FCC, FDA, HALAL, KOSHER).
Plant Extract: Nature-Derived Ingredients for Better Health. Weight Loss, Male & Female Supplements, Immune Boost, Eye Health. Direct factory & Custom Formulas.
Nutritional Supplement Raw Materials: Power Your Supplements with Premium Ingredients. Amino Acids, Vitamins, Minerals, Probiotics, Natural Fruit & Vegetable Powder, Sweeteners. Global Certified & OEM Support.
Cosmetic Raw Materials: Cosmetic Ingredients & Cosmetic Peptides. Cleansing, Sunscreen, Anti-Aging, Antioxidant, Spot Removal & Whitening, Exfoliation, Beauty & Skin Enhancing.
Pharmaceutical Intermediates: Promote Your Production with Quality Intermediates. GMP Standard and ISO9001 Stable Quality.
Below is our signature lineup of biological active ingredients, manufactured under strict quality controls.







