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S‑Adenosylmethionine (SAM) is an organic compound synthesized from methionine and adenosine triphosphate (ATP) under the catalysis of methionine adenosyltransferase. Its CAS number is 485-80-3, with molecular formula and molecular weight of 399.445.
As the biologically active form of methionine, SAM naturally occurs in animals and plants and serves as a coenzyme for over 100 methyltransferases. It is clinically used for adjunctive treatment of liver diseases, depression and osteoarthritis.
| Items | Standards | Results |
|---|---|---|
| Physical Analysis | ||
| Appearance | Fine Powder | Conforms |
| Color | Brown Yellow | Conforms |
| Odor | Characteristic | Conforms |
| Mesh Size | 100% through 80 mesh | Conforms |
| General Analysis | ||
| Identification | Identical to R.S. sample | Conforms |
| Rosmarinic Acid | ≥90.0% | Conforms |
| Moisture | ≤5.0% | Conforms |
| Total heavy metals | ≤10.0ppm | Conforms |
| Pb | ≤2.0ppm | Conforms |
| As | ≤10.0 | Conforms |
| Cd | ≤1.0ppm | Conforms |
| Hg | ≤0.1ppm | Conforms |
| Microbiological Analysis | ||
| Total Plate Count(cfu/g) | ≤1,000 | Conforms |
| Molds and Yeast (cfu/g) | ≤100 | Conforms |
| Coliforms (cfu/g) | Negative | Conforms |
| Salmonella(/25g) | Negative | Conforms |
| Weight | Packing method |
|---|---|
| 1kg | bag/kg, box outside (double plastic bag + Aluminum foil bag inside) |
| 10kgs, 25kg or more | by Drums or carton (2 layers plastic bag inside) |
| Weight | Delivery method | Delivery time | Destination |
|---|---|---|---|
| 1kg-25kgs | EMS, DHL, UPS, Fedex | 3-7days | Door to door |
| 25kgs-100kgs | DHL, FedEx, by Air | 3-7days | Door to door (to Airport by Air) |
| more than 100kgs | by Air | 3-7days | Door to Airport |
| by Sea | 10-35days | Door to port |
