High-Quality Natural Nattokinase Supplement from China Suppliers - High-Quality Nitto Extract Factory Product Supplier, Company

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Product Name

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Nattokinase

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Plant Sources

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Nitto Extract

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Appearance

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Light yellow to white fine powder

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Specification

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20000 FU/G

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Test Method

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HPLC/UV

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Country of Origin

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China

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Looking for high-quality Nattokinase? As a leading supplier from China, we are a trusted factory providing premium Nattokinase extracted from Nitto. Our product features a fine powder appearance and a specification of 20000 FU/G, verified by rigorous HPLC/UV testing. Interested in our Nattokinase or other products? Contact us today for free samples and discover why we are a preferred choice among suppliers!

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Product Description

Product Description
Nattokinase-1
Nattokinase, also known as subtilisin (hereinafter referred to as NK), is a serine protease produced by Bacillus subtilis natto during the fermentation of natto. It can dissolve thrombi, reduce blood viscosity, improve blood circulation, soften blood vessels and enhance vascular elasticity.
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Advanced Fermentation Technology: Produced via liquid fermentation and nanobiotechnology, enabling precise extraction of active ingredients. The product's kinase activity exceeds 50,000 Fu/g.
Superior Advantages: Compared with other thrombolytic drugs, Nattokinase (NK) offers advantages including low cost, high safety, small molecular weight, excellent oral efficacy, strong thrombolytic activity and long duration of action.
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Optimal Reaction Conditions: Temperature: 30–45°C (best at 37°C); denatures above 80°C. pH: 6–9 (best at pH 7.4); inactivates below pH 5.
Production Process
Bacillus subtilis natto fermentation → Extraction → Horizontal spiral separation → Centrate → High-speed tubular centrifugation → Centrate → Microfiltration → Ultrafiltration ↖ Re-extraction Residue ↓ Discarding → Vacuum freeze-drying → Shatter → Blend → Detection → Packaging → Finished Product ↑ ↑ Acceptance Acceptance ↑ ↑ Excipients Inner packaging bag
💡 Enzyme Activity Definition: Nattokinase reacts with fibrin to hydrolyze the peptide bonds of fibrin. The hydrolysis reaction changes the absorbance of the solution at 275 nm of ultraviolet light. One activity unit (1 FU) refers to the energy consumed for every 0.01 increase in the absorbance value at 275 nm.
Certificate of Analysis
Appearance Fine Powder Conforms NLS-QCS-1008
Color Yellow white-off white Conforms GB/T 5492-2008
Odor Characteristic Conforms GB/T 5492-2008
Taste Characteristic Conforms GB/T 5492-2008
Part Used Seeds Conforms /
Drying Method Freeze drying Conforms /
Physical Characteristics
Particle Size (80 mesh) NLT 95% through 80 mesh Conform GB/T 5507-2008
Moisture <5.0% 3.8% GB/T 14769-1993
Ash Content <5.0% 2.6% AOAC 942.05, 18th
Solvent Residue Eur Pharm Conform NLS-QCS-1007
Heavy Metals
Total Heavy Metals <10ppm Conform USP <231>, method II
As <2.0ppm Conform AOAC 986.15, 18th
Pb <2.0ppm Conform AOAC 986.15, 18th
Cd <0.5ppm Conform AOAC 986.15, 18th
Hg <0.5ppm Conform AOAC 971.21, 18th
Pesticide Residue
666 <0.2ppm Conform GB/T5009.19-1996
DDT <0.2ppm Conform GB/T5009.19-1996
Microbiological Tests
Total Plate Count <1,000cfu/g Conform AOAC 990.12, 18th
Total Yeast & Mold <100cfu/g Conform FDA (BAM) Chapter 18, 8th Ed.
E. Coli Negative Negative AOAC 997.11, 18th
Salmonella Negative Negative FDA (BAM) Chapter 5, 8th Ed.
Effects of Different Factors on Enzyme Activity
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Functions & Applications
  • ❤️
    Nattokinase helps dissolve blood clots and lower blood lipids, making it highly effective in protecting against and supporting cardiovascular and cerebrovascular health.
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    It supports healthy hormone balance, aids detoxification, improves skin appearance, and assists with weight and fat management.
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    It also offers antioxidant and anti-fatigue benefits, helping to slow down the aging process.
  • 💊
    Absorbed easily through the intestines, it boosts thrombolytic activity in the body, reduces the risk of heart attack, and supports stronger heart function.
Application of Nattokinase
Application of Nattokinase 1
Storage

❄️ Keep in a cool, dry and dark place. Storage temperature: below 0°C.

⚠️ Prolonged or improper storage may reduce enzyme activity. If exposed to high temperature or humidity, an appropriate increase in dosage is recommended.

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Packing
Weight Packing Method
1kg Bag/kg, box outside (double plastic bag + aluminum foil bag inside)
10kgs, 25kg or more By drums or carton (2 layers plastic bag inside)
packaging
Delivery
Weight Delivery Method Delivery Time Destination
1kg – 25kgs EMS, DHL, UPS, FedEx 3–7 days Door to door
25kgs – 100kgs DHL, FedEx, by Air 3–7 days Door to door (to Airport by Air)
More than 100kgs By Air 3–7 days Door to Airport
By Sea 10–35 days Door to port
Logistics
Logistics
Frequently Asked Questions (FAQ)
Q What is Nattokinase and where does it come from?
Nattokinase (NK) is a serine protease naturally produced by Bacillus subtilis natto during the fermentation of soybeans (natto). It is extracted and purified using liquid fermentation combined with nanobiotechnology to achieve high enzymatic activity exceeding 50,000 Fu/g.
Q What are the main health benefits of Nattokinase?
Nattokinase helps dissolve blood clots, reduces blood viscosity, improves blood circulation, and softens blood vessels. It also supports cardiovascular and cerebrovascular health, promotes hormone balance, assists in detoxification and weight management, and offers antioxidant and anti-fatigue benefits.
Q What are the optimal temperature and pH conditions for Nattokinase activity?
The optimal reaction temperature range is 30–45°C, with peak performance at 37°C. The enzyme denatures and inactivates above 80°C. The optimal pH range is 6–9, with best performance at pH 7.4. Enzyme activity is lost below pH 5.
Q How should Nattokinase be stored to maintain its activity?
Nattokinase should be stored in a cool, dry, and dark environment at temperatures below 0°C. Prolonged or improper storage — especially exposure to high temperatures or humidity — may reduce enzyme activity. In such cases, a slight increase in dosage is recommended.
Q What packaging options and minimum order quantities are available?
Nattokinase is available in 1 kg bags (double plastic bag + aluminum foil bag inside a box) as well as 10 kg, 25 kg, or larger quantities packaged in drums or cartons with two layers of plastic bags inside. Custom packaging arrangements can be discussed based on order volume.
Q What shipping methods are available and what are the delivery times?
For orders of 1–25 kg, express courier services (EMS, DHL, UPS, FedEx) are available with a delivery time of 3–7 days door-to-door. Orders of 25–100 kg ship via DHL, FedEx, or air freight in 3–7 days. Orders over 100 kg can be shipped by air (3–7 days, door to airport) or by sea (10–35 days, door to port).

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