High-Quality Nattokinase Supplement from China - High-Quality Nitto Extract Factory Suppliers Manufacturer, Suppliers

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Product Name

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Nattokinase

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Plant Source

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Nitto Extract

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Appearance

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Light yellow to white fine powder

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Specification

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20000 FU/G

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Test Method

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HPLC/UV

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Country of Origin

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China

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Discover premium Nattokinase from trusted suppliers in China. Our product is meticulously sourced and processed in our state-of-the-art factory, ensuring high quality and efficacy. Interested in our offerings? Contact us for free samples today!

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Product Description

Product Description
Nattokinase-1

Nattokinase, also known as subtilisin (hereinafter referred to as NK), is a serine protease produced by Bacillus subtilis natto during the fermentation of natto. It can dissolve thrombi, reduce blood viscosity, improve blood circulation, soften blood vessels and enhance vascular elasticity.

Product Features
① High Activity: Produced via liquid fermentation and nanobiotechnology, enabling precise extraction of active ingredients. The product's kinase activity exceeds 50,000 Fu/g.
② Superior Advantages: Compared with other thrombolytic drugs, Nattokinase (NK) offers advantages including low cost, high safety, small molecular weight, excellent oral efficacy, strong thrombolytic activity and long duration of action.
③ Optimal Conditions: Optimal reaction temperature: 30–45°C, with the best performance at 37°C; denatures and inactivates above 80°C. Optimal reaction pH: 6–9, with the best performance at pH 7.4; inactivates below pH 5.
Production Process
Bacillus subtilis natto fermentation → Extraction → Horizontal spiral separation → Centrate
→ High-speed tubular centrifugation → Centrate → Microfiltration → Ultrafiltration
                                              ↑
                                Re-extraction ← Residue → Discarding

→ Vacuum freeze-drying → Shatter → Blend → Detection → Packaging → Finished Product
                                ↑                ↑
                                acceptance    acceptance
                                      ↑                ↑
                              Excipients  Inner packaging bag
🔬 Enzyme Activity Definition: Nattokinase reacts with fibrin to hydrolyze the peptide bonds of fibrin. The hydrolysis reaction changes the absorbance of the solution at 275 nm of ultraviolet light. One activity unit (1 FU) refers to the energy consumed for every 0.01 increase in the absorbance value at 275 nm.
Certificate of Analysis
AppearanceFine PowderConformsNLS-QCS-1008
ColorYellow white – off whiteConformsGB/T 5492-2008
OdorCharacteristicConformsGB/T 5492-2008
TasteCharacteristicConformsGB/T 5492-2008
Part UsedSeedsConforms/
Drying MethodFreeze dryingConforms/
Physical Characteristics
Particle Size (80 mesh)NLT 95% through 80 meshConformGB/T 5507-2008
Moisture<5.0%3.8%GB/T 14769-1993
Ash Content<5.0%2.6%AOAC 942.05, 18th
Solvent ResidueEur PharmConformNLS-QCS-1007
Heavy Metals
Total Heavy Metals<10ppmConformUSP <231>, method II
As<2.0ppmConformAOAC 986.15, 18th
Pb<2.0ppmConformAOAC 986.15, 18th
Cd<0.5ppmConformAOAC 986.15, 18th
Hg<0.5ppmConformAOAC 971.21, 18th
Pesticide Residue
666<0.2ppmConformGB/T5009.19-1996
DDT<0.2ppmConformGB/T5009.19-1996
Microbiological Tests
Total Plate Count<1,000 cfu/gConformAOAC 990.12, 18th
Total Yeast & Mold<100 cfu/gConformFDA (BAM) Chapter 18, 8th Ed.
E. ColiNegativeNegativeAOAC 997.11, 18th
SalmonellaNegativeNegativeFDA (BAM) Chapter 5, 8th Ed.
Effects of Different Factors on Enzyme Activity
product description01
product description02
Functions & Applications
  • Nattokinase helps dissolve blood clots and lower blood lipids, making it highly effective in protecting against and supporting cardiovascular and cerebrovascular health.
  • It supports healthy hormone balance, aids detoxification, improves skin appearance, and assists with weight and fat management.
  • It also offers antioxidant and anti-fatigue benefits, helping to slow down the aging process.
  • Absorbed easily through the intestines, it boosts thrombolytic activity in the body, reduces the risk of heart attack, and supports stronger heart function.
Application of Nattokinase
Application of Nattokinase 1
Storage
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Keep in a cool, dry and dark place. Storage temperature: below 0°C.
Prolonged or improper storage may reduce enzyme activity. If exposed to high temperature or humidity, an appropriate increase in dosage is recommended.
Production workshop 1
Production workshop 2
Production workshop 3
Packing
WeightPacking Method
1 kgBag/kg, box outside (double plastic bag + aluminum foil bag inside)
10 kgs, 25 kg or moreBy drums or carton (2 layers plastic bag inside)
packaging
Delivery
WeightDelivery MethodDelivery TimeDestination
1 kg – 25 kgsEMS, DHL, UPS, FedEx3–7 daysDoor to door
25 kgs – 100 kgsDHL, FedEx, by Air3–7 daysDoor to door (to Airport by Air)
More than 100 kgsBy Air3–7 daysDoor to Airport
By Sea10–35 daysDoor to port
Logistics
Logistics
Frequently Asked Questions (FAQ)
Q
What is Nattokinase and where does it come from?
Nattokinase (NK) is a serine protease extracted from natto, a traditional Japanese fermented soybean food. It is produced by Bacillus subtilis natto during the fermentation process and is known for its potent thrombolytic properties.
Q
What is the enzyme activity level of your Nattokinase product?
Our Nattokinase is produced via liquid fermentation combined with nanobiotechnology. The kinase activity exceeds 50,000 Fu/g, ensuring a highly potent and effective product for various applications.
Q
What are the optimal storage conditions for Nattokinase?
Nattokinase should be stored in a cool, dry, and dark environment at temperatures below 0°C. Exposure to high temperatures (above 80°C) or extreme humidity may cause denaturation and reduce enzyme activity.
Q
What are the main health benefits and applications of Nattokinase?
Nattokinase offers a wide range of health benefits, including: dissolving blood clots and lowering blood lipids to support cardiovascular health; promoting hormonal balance and detoxification; providing antioxidant and anti-fatigue effects; and boosting thrombolytic activity in the body.
Q
What packaging and shipping options are available?
We offer flexible packaging options: 1 kg orders are packed in double plastic bags with an aluminum foil inner bag; larger orders are shipped in drums or cartons with two inner plastic bag layers. Delivery is available via EMS, DHL, UPS, FedEx, Air Freight, or Sea Freight.
Q
Does your Nattokinase pass microbiological and heavy metal safety testing?
Yes. Our Nattokinase undergoes rigorous quality control testing, conforming to strict limits for heavy metals, pesticide residues, and microbiological standards. Tests for E. Coli and Salmonella return negative results.

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