High-Quality Natural Nattokinase Supplement from China - Quality Nitto Extract by Reliable Suppliers and Factory Manufacturers, Suppliers

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High-Quality Natural Nattokinase Supplement from China - Quality Nitto Extract by Reliable Suppliers and Factory Manufacturers, Suppliers

, , , , , , , , , , , , , , , , , , , , , , , , , , , ,

, Product Name ,	, Nattokinase ,
, Plant Source ,	, Nitto Extract ,
, Appearance ,	, Light yellow to white fine powder ,
, Specification ,	, 20000 FU/G ,
, Test Method ,	, HPLC/UV ,
, Country of Origin ,	, China ,

Looking for high-quality Nattokinase? As a leading manufacturer and supplier from China, we provide premium Nattokinase sourced from Nitto Extract. Our product is a light yellow to white fine powder with a specification of 20000 FU/G, tested using HPLC/UV methods for quality assurance. Interested in sampling our product? Contact us today for free samples directly from our factory.

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Product Description

Product Description

Nattokinase, also known as subtilisin (hereinafter referred to as NK), is a serine protease produced by Bacillus subtilis natto during the fermentation of natto. It can dissolve thrombi, reduce blood viscosity, improve blood circulation, soften blood vessels and enhance vascular elasticity.

Product Features

Produced via liquid fermentation and nanobiotechnology, enabling precise extraction of active ingredients. The product's kinase activity exceeds 50,000 Fu/g.

Compared with other thrombolytic drugs, Nattokinase (NK) offers advantages including low cost, high safety, small molecular weight, excellent oral efficacy, strong thrombolytic activity and long duration of action.

Optimal reaction temperature: 30–45°C, with the best performance at 37°C; denatures and inactivates above 80°C. Optimal reaction pH: 6–9, with the best performance at pH 7.4; inactivates below pH 5.

Production Process

Bacillus subtilis natto fermentation → Extraction → Horizontal spiral separation → Centrate → High-speed tubular centrifugation → Centrate → Microfiltration → Ultrafiltration ↑ Re-extraction ← Residue ↓ Discarding → Vacuum freeze-drying → Shatter → Blend → Detection → Packaging → Finished Product ↑ ↑ Acceptance Acceptance ↑ ↑ Excipients Inner packaging bag

💡 Enzyme Activity Definition: Nattokinase reacts with fibrin to hydrolyze the peptide bonds of fibrin. The hydrolysis reaction changes the absorbance of the solution at 275 nm of ultraviolet light. One activity unit (1FU) refers to the energy consumed for every 0.01 increase in the absorbance value at 275 nm.

Certificate of Analysis

Appearance	Fine Powder	Conforms	NLS-QCS-1008
Color	Yellow white-off white	Conforms	GB/T 5492-2008
Odor	Characteristic	Conforms	GB/T 5492-2008
Taste	Characteristic	Conforms	GB/T 5492-2008
Part Used	Seeds	Conforms	/
Drying Method	Freeze drying	Conforms	/
Physical Characteristics
Particle Size (80 mesh)	NLT 95% through 80 mesh	Conform	GB/T 5507-2008
Moisture	<5.0%	3.8%	GB/T 14769-1993
Ash Content	<5.0%	2.6%	AOAC 942.05, 18th
Solvent Residue	Eur Pharm	Conform	NLS-QCS-1007
Heavy Metals
Total Heavy Metals	<10ppm	Conform	USP <231>, method II
As	<2.0ppm	Conform	AOAC 986.15, 18th
Pb	<2.0ppm	Conform	AOAC 986.15, 18th
Cd	<0.5ppm	Conform	AOAC 986.15, 18th
Hg	<0.5ppm	Conform	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GB/T5009.19-1996
DDT	<0.2ppm	Conform	GB/T5009.19-1996
Microbiological Tests
Total Plate Count	<1,000cfu/g	Conform	AOAC 990.12, 18th
Total Yeast & Mold	<100cfu/g	Conform	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997.11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

Effects of Different Factors on Enzyme Activity

Functions & Applications

🫀

Nattokinase helps dissolve blood clots and lower blood lipids, making it highly effective in protecting against and supporting cardiovascular and cerebrovascular health.

⚖️

It supports healthy hormone balance, aids detoxification, improves skin appearance, and assists with weight and fat management.

🛡️

It also offers antioxidant and anti-fatigue benefits, helping to slow down the aging process.

💊

Absorbed easily through the intestines, it boosts thrombolytic activity in the body, reduces the risk of heart attack, and supports stronger heart function.

Storage

❄️

Keep in a cool, dry and dark place. Storage temperature: below 0°C.

Prolonged or improper storage may reduce enzyme activity. If exposed to high temperature or humidity, an appropriate increase in dosage is recommended.

Packing

Weight	Packing Method
1kg	Bag/kg, box outside (double plastic bag + Aluminum foil bag inside)
10kgs, 25kg or more	By Drums or carton (2 layers plastic bag inside)

Delivery

Weight	Delivery Method	Delivery Time	Destination
1kg–25kgs	EMS, DHL, UPS, FedEx	3–7 days	Door to door
25kgs–100kgs	DHL, FedEx, by Air	3–7 days	Door to door (to Airport by Air)
More than 100kgs	By Air	3–7 days	Door to Airport
More than 100kgs	By Sea	10–35 days	Door to port

Logistics

❓ Frequently Asked Questions (FAQ)

What is Nattokinase and how is it produced?

Nattokinase (NK) is a serine protease derived from Bacillus subtilis natto during the fermentation of natto. It is produced through liquid fermentation combined with nanobiotechnology, which allows for precise extraction of active ingredients and ensures kinase activity exceeding 50,000 Fu/g.

What are the main health benefits of Nattokinase?

Nattokinase offers a wide range of benefits: it dissolves blood clots, lowers blood lipids, improves blood circulation, supports cardiovascular and cerebrovascular health, aids hormone balance, helps with detoxification, improves skin appearance, provides antioxidant and anti-fatigue effects, and assists with weight management.

What are the optimal conditions for Nattokinase enzyme activity?

The optimal reaction temperature for Nattokinase is between 30–45°C, with peak performance at 37°C. It denatures and becomes inactive above 80°C. The optimal pH range is 6–9, with best performance at pH 7.4. The enzyme inactivates below pH 5.

How should Nattokinase be stored?

Nattokinase should be kept in a cool, dry, and dark place at a storage temperature below 0°C. Prolonged or improper storage may reduce enzyme activity. If the product has been exposed to high temperature or humidity, it is recommended to increase the dosage appropriately to compensate.

What packaging options are available for Nattokinase?

For small quantities (1kg), the product is packaged in a bag per kg with a box outside, using double plastic bags plus an aluminum foil bag inside. For larger quantities (10kg, 25kg or more), it is packaged in drums or cartons with 2 layers of plastic bags inside to ensure product integrity during transport.

What shipping methods and delivery times are available?

For orders of 1–25kg, shipments are made via EMS, DHL, UPS, or FedEx with door-to-door delivery in 3–7 days. For 25–100kg, DHL, FedEx, or air freight is used. For orders over 100kg, air freight (3–7 days, door to airport) or sea freight (10–35 days, door to port) is available.

Product Detail

High-Quality Natural Nattokinase Supplement from China - Quality Nitto Extract by Reliable Suppliers and Factory Manufacturers, Suppliers

Product Description

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