Wholesale Nattokinase Supplement from China Suppliers - Natural Natto Extract by Trusted Factory, 20000FU/G Quality Exporters, Factories

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Wholesale Nattokinase Supplement from China Suppliers - Natural Natto Extract by Trusted Factory, 20000FU/G Quality Exporters, Factories

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, Product Name ,	, Nattokinase ,
, Plant Sources ,	, Nitto Extract ,
, Appearance ,	, Light yellow to white fine powder ,
, Specification ,	, 20000 FU/G ,
, Test Method ,	, HPLC/UV ,
, Country of Origin ,	, China ,

Looking for high-quality Nattokinase? As a leading manufacturer and supplier in China, we provide premium products directly from our factory. Interested in trying our offerings? Contact us for free samples today!

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Product Description

Nattokinase, also known as subtilisin (hereinafter referred to as NK), is a serine protease produced by Bacillus subtilis natto during the fermentation of natto. It can dissolve thrombi, reduce blood viscosity, improve blood circulation, soften blood vessels and enhance vascular elasticity.

Product Features

Produced via liquid fermentation and nanobiotechnology, enabling precise extraction of active ingredients. The product's kinase activity exceeds 50,000 Fu/g.

Compared with other thrombolytic drugs, Nattokinase (NK) offers advantages including low cost, high safety, small molecular weight, excellent oral efficacy, strong thrombolytic activity and long duration of action.

Optimal reaction temperature: 30–45°C, with the best performance at 37°C; denatures and inactivates above 80°C. Optimal reaction pH: 6–9, with the best performance at pH 7.4; inactivates below pH 5.

Production Process

Bacillus subtilis natto fermentation → Extraction → Horizontal spiral separation → Centrate → High-speed tubular centrifugation → Centrate → Microfiltration → Ultrafiltration
Re-extraction ↗                                  ↖
Residue                                           ↓
Discarding → Vacuum freeze-drying → Shatter → Blend → Detection → Packaging → Finished Product
                                                         ↑                ↑
                                                      Acceptance    Acceptance
                                                         ↑                ↑
                                                     Excipients     Inner packaging bag

Enzyme Activity Definition: Nattokinase reacts with fibrin to hydrolyze the peptide bonds of fibrin. The hydrolysis reaction changes the absorbance of the solution at 275 nm of ultraviolet light. One activity unit (1 FU) refers to the energy consumed for every 0.01 increase in the absorbance value at 275 nm.

Certificate of Analysis

Appearance	Fine Powder	Conforms	NLS-QCS-1008
Color	Yellow white-off white	Conforms	GB/T 5492-2008
Odor	Characteristic	Conforms	GB/T 5492-2008
Taste	Characteristic	Conforms	GB/T 5492-2008
Part Used	Seeds	Conforms	/
Drying Method	Freeze drying	Conforms	/
Physical Characteristics
Particle Size (80 mesh)	NLT 95% through 80 mesh	Conform	GB/T 5507-2008
Moisture	<5.0%	3.8%	GB/T 14769-1993
Ash Content	<5.0%	2.6%	AOAC 942.05, 18th
Solvent Residue	Eur Pharm	Conform	NLS-QCS-1007
Heavy Metals
Total Heavy Metals	<10ppm	Conform	USP <231>, method II
As	<2.0ppm	Conform	AOAC 986.15, 18th
Pb	<2.0ppm	Conform	AOAC 986.15, 18th
Cd	<0.5ppm	Conform	AOAC 986.15, 18th
Hg	<0.5ppm	Conform	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GB/T5009.19-1996
DDT	<0.2ppm	Conform	GB/T5009.19-1996
Microbiological Tests
Total Plate Count	<1,000cfu/g	Conform	AOAC 990.12, 18th
Total Yeast & Mold	<100cfu/g	Conform	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997.11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

Effects of Different Factors on Enzyme Activity

Functions & Applications

🩸

Nattokinase helps dissolve blood clots and lower blood lipids, making it highly effective in protecting against and supporting cardiovascular and cerebrovascular health.

⚖️

It supports healthy hormone balance, aids detoxification, improves skin appearance, and assists with weight and fat management.

🛡️

It also offers antioxidant and anti-fatigue benefits, helping to slow down the aging process.

💊

Absorbed easily through the intestines, it boosts thrombolytic activity in the body, reduces the risk of heart attack, and supports stronger heart function.

Storage

🌡️ Keep in a cool, dry and dark place. Storage temperature: below 0°C.

⚠️ Prolonged or improper storage may reduce enzyme activity. If exposed to high temperature or humidity, an appropriate increase in dosage is recommended.

Packing

Weight	Packing Method
1kg	Bag/kg, box outside (double plastic bag + aluminum foil bag inside)
10kgs, 25kg or more	By drums or carton (2 layers plastic bag inside)

Delivery

Weight	Delivery Method	Delivery Time	Destination
1kg – 25kgs	EMS, DHL, UPS, FedEx	3–7 days	Door to door
25kgs – 100kgs	DHL, FedEx, by Air	3–7 days	Door to door (to Airport by Air)
More than 100kgs	By Air	3–7 days	Door to Airport
More than 100kgs	By Sea	10–35 days	Door to port

Logistics

❓ Frequently Asked Questions (FAQ)

What is Nattokinase and where does it come from?

Nattokinase (NK) is a serine protease naturally produced by Bacillus subtilis natto during the fermentation of soybeans into natto, a traditional Japanese food. It is extracted and purified for use as a dietary supplement due to its potent thrombolytic properties.

What is the enzyme activity level of your Nattokinase product?

Our Nattokinase is produced using advanced liquid fermentation combined with nanobiotechnology. The kinase activity of our product exceeds 50,000 Fu/g, ensuring high potency and consistent performance in every batch.

What are the main health benefits of Nattokinase?

Nattokinase offers multiple health benefits: it helps dissolve blood clots, reduces blood viscosity, improves circulation, softens blood vessels, supports cardiovascular and cerebrovascular health, aids hormone balance and detoxification, provides antioxidant and anti-fatigue effects, and assists with weight management.

What are the optimal storage conditions for Nattokinase?

Nattokinase should be stored in a cool, dry, and dark environment at temperatures below 0°C. Exposure to high temperatures (above 80°C) or extreme humidity may reduce enzyme activity. If storage conditions are not ideal, a slight increase in dosage may be appropriate to compensate for any activity loss.

What packaging options are available and how is the product shipped?

We offer flexible packaging: 1kg orders are packed in a double plastic bag with aluminum foil lining inside a box; larger orders (10kg, 25kg or more) are packed in drums or cartons with 2-layer plastic bag protection. Shipping options include EMS, DHL, UPS, FedEx for small orders (1–25kg), and air or sea freight for larger volumes (25kg–100kg and above), with delivery times ranging from 3–7 days (air) to 10–35 days (sea).

How is your Nattokinase quality tested and verified?

Each batch of our Nattokinase undergoes rigorous quality testing in accordance with internationally recognized standards including USP, AOAC, FDA (BAM), and Chinese national standards (GB/T). Tests cover appearance, physical characteristics, heavy metals (As, Pb, Cd, Hg), pesticide residues, and comprehensive microbiological screening to ensure safety and compliance.

Product Detail

Wholesale Nattokinase Supplement from China Suppliers - Natural Natto Extract by Trusted Factory, 20000FU/G Quality Exporters, Factories

Product Description

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Wholesale Nattokinase Supplement from China Suppliers - Natural Natto Extract by Trusted Factory, 20000FU/G Quality Exporters, Factories

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