Wholesale China Nattokinase Supplement from Factory Suppliers - Natural Natto Extract with 20000FU/G Quality Manufacturers, Exporter

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Product Name

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Nattokinase

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Plant Sources

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Nitto Extract

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Appearance

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Light yellow to white fine powder

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Specification

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20000 FU/G

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Test Method

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HPLC/UV

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Country of Origin

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China

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Looking for a reliable source of Nattokinase? Our factory in China is a leading supplier of high-quality Nattokinase derived from Nitto Extract. This light yellow to white fine powder packs an impressive specification of 20000 FU/G and is tested using advanced HPLC/UV methods for guaranteed purity. Interested in our products? Contact us today for free samples and discover the excellence we offer as trusted suppliers from China.

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Product Description

Product Description
Nattokinase-1

Nattokinase, also known as subtilisin (hereinafter referred to as NK), is a serine protease produced by Bacillus subtilis natto during the fermentation of natto. It can dissolve thrombi, reduce blood viscosity, improve blood circulation, soften blood vessels and enhance vascular elasticity.

★ Product Features
  • Produced via liquid fermentation and nanobiotechnology, enabling precise extraction of active ingredients. The product's kinase activity exceeds 50,000 Fu/g.
  • Compared with other thrombolytic drugs, Nattokinase (NK) offers advantages including low cost, high safety, small molecular weight, excellent oral efficacy, strong thrombolytic activity and long duration of action.
  • Optimal reaction temperature: 30–45°C, best performance at 37°C; denatures above 80°C. Optimal pH: 6–9, best at pH 7.4; inactivates below pH 5.
Production Process
Bacillus subtilis natto fermentation Extraction Horizontal spiral separation Centrate High-speed tubular centrifugation Centrate Microfiltration Ultrafiltration
 ↗ Re-extraction ← Residue → Discarding
Vacuum freeze-drying Shatter Blend Detection Packaging Finished Product
 ↑ Acceptance (Excipients) ↑ Acceptance (Inner packaging bag)
💡 Enzyme Activity Definition: Nattokinase reacts with fibrin to hydrolyze its peptide bonds, changing the solution's absorbance at 275 nm UV light. One activity unit (1 FU) refers to the energy consumed for every 0.01 increase in absorbance at 275 nm.
Certificate of Analysis
Item Specification Result Method
Appearance Fine Powder Conforms NLS-QCS-1008
Color Yellow white-off white Conforms GB/T 5492-2008
Odor Characteristic Conforms GB/T 5492-2008
Taste Characteristic Conforms GB/T 5492-2008
Part Used Seeds Conforms /
Drying Method Freeze drying Conforms /
Physical Characteristics
Particle Size (80 mesh) NLT 95% through 80 mesh Conform GB/T 5507-2008
Moisture <5.0% 3.8% GB/T 14769-1993
Ash Content <5.0% 2.6% AOAC 942.05, 18th
Solvent Residue Eur Pharm Conform NLS-QCS-1007
Heavy Metals
Total Heavy Metals <10ppm Conform USP <231>, method II
As <2.0ppm Conform AOAC 986.15, 18th
Pb <2.0ppm Conform AOAC 986.15, 18th
Cd <0.5ppm Conform AOAC 986.15, 18th
Hg <0.5ppm Conform AOAC 971.21, 18th
Pesticide Residue
666 <0.2ppm Conform GB/T5009.19-1996
DDT <0.2ppm Conform GB/T5009.19-1996
Microbiological Tests
Total Plate Count <1,000cfu/g Conform AOAC 990.12, 18th
Total Yeast & Mold <100cfu/g Conform FDA (BAM) Chapter 18, 8th Ed.
E. Coli Negative Negative AOAC 997.11, 18th
Salmonella Negative Negative FDA (BAM) Chapter 5, 8th Ed.
Effects of Different Factors on Enzyme Activity
product description01
product description02
Functions & Applications
  • ❤️ Nattokinase helps dissolve blood clots and lower blood lipids, making it highly effective in protecting against and supporting cardiovascular and cerebrovascular health.
  • 🌿 It supports healthy hormone balance, aids detoxification, improves skin appearance, and assists with weight and fat management.
  • 💪 It also offers antioxidant and anti-fatigue benefits, helping to slow down the aging process.
  • 💊 Absorbed easily through the intestines, it boosts thrombolytic activity, reduces the risk of heart attack, and supports stronger heart function.
Application of Nattokinase
Application of Nattokinase 1
Storage
❄️ Keep in a cool, dry and dark place. Storage temperature: below 0°C.
⚠️ Prolonged or improper storage may reduce enzyme activity. If exposed to high temperature or humidity, an appropriate increase in dosage is recommended.
Production Workshop 1
Production Workshop 2
Production Workshop 3
Packing
Weight Packing Method
1kg Bag/kg, box outside (double plastic bag + aluminum foil bag inside)
10kgs, 25kg or more By drums or carton (2 layers plastic bag inside)
Packaging
Delivery
Weight Delivery Method Delivery Time Destination
1kg – 25kgs EMS, DHL, UPS, FedEx 3–7 days Door to door
25kgs – 100kgs DHL, FedEx, by Air 3–7 days Door to door (to Airport by Air)
More than 100kgs By Air 3–7 days Door to Airport
By Sea 10–35 days Door to port
Logistics
Logistics
Frequently Asked Questions (FAQ)
Q What is Nattokinase and where does it come from?
A Nattokinase (NK) is a serine protease naturally produced by Bacillus subtilis natto during the fermentation process of natto (a traditional Japanese soybean food). It is extracted using liquid fermentation and nanobiotechnology to ensure high purity and potency.
Q What is the enzyme activity level of your Nattokinase product?
A Our Nattokinase product has a kinase activity exceeding 50,000 FU/g (Fibrinolytic Units per gram), ensuring highly effective thrombolytic performance for health and supplement applications.
Q What are the main health benefits of Nattokinase?
A Nattokinase supports cardiovascular and cerebrovascular health by dissolving blood clots, lowering blood lipids, and improving circulation. It also offers antioxidant, anti-fatigue, hormone-balancing, and skin-improving benefits, and helps reduce the risk of heart attack.
Q What are the optimal storage conditions for Nattokinase?
A Nattokinase should be stored in a cool, dry, and dark environment at temperatures below 0°C. Exposure to high temperatures (above 80°C) or acidic conditions (below pH 5) will cause denaturation and loss of enzyme activity. If storage conditions are suboptimal, increasing the dosage slightly is recommended.
Q What packing and shipping options are available?
A We offer flexible packaging from 1kg (aluminum foil bag inside a box) to bulk 25kg drums or cartons. Shipping is available worldwide via EMS, DHL, UPS, FedEx, air freight, or sea freight, with delivery times ranging from 3–7 days (express/air) to 10–35 days (sea).
Q Does your Nattokinase meet international quality and safety standards?
A Yes. Our Nattokinase passes rigorous quality testing including physical characteristics, heavy metal limits (USP, AOAC standards), pesticide residue tests, and full microbiological testing (E. Coli and Salmonella negative). All results conform to international standards including GB, AOAC, USP, and FDA BAM methods.

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