Wholesale Natural Nattokinase Supplement from China: Top Suppliers & Factory Direct Products Manufacturer, Factories

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Product Name

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Nattokinase

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Plant Sources

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Nitto Extract

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Appearance

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Light yellow to white fine powder

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Specification

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20,000 FU/G

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Test Method

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HPLC/UV

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Country of Origin

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China

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Looking for quality Nattokinase from reliable suppliers? Our factory in China offers top-grade Nattokinase with a specification of 20,000 FU/G. Available as a light yellow to white fine powder, it is obtained from premium Nitto Extract. Contact us today to request free samples and learn more about our products!

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Product Description

Product Description
Nattokinase-1
Nattokinase, also known as subtilisin (hereinafter referred to as NK), is a serine protease produced by Bacillus subtilis natto during the fermentation of natto. It can dissolve thrombi, reduce blood viscosity, improve blood circulation, soften blood vessels and enhance vascular elasticity.
Product Features
1
Produced via liquid fermentation and nanobiotechnology, enabling precise extraction of active ingredients. The product's kinase activity exceeds 50,000 Fu/g.
2
Compared with other thrombolytic drugs, Nattokinase (NK) offers advantages including low cost, high safety, small molecular weight, excellent oral efficacy, strong thrombolytic activity and long duration of action.
3
Optimal reaction temperature: 30–45°C, with the best performance at 37°C; denatures and inactivates above 80°C. Optimal reaction pH: 6–9, with the best performance at pH 7.4; inactivates below pH 5.
Production Process
Bacillus subtilis natto fermentation → Extraction → Horizontal spiral separation → Centrate → High-speed tubular centrifugation → Centrate → Microfiltration → Ultrafiltration ↑ Re-extraction ← Residue ↓ Discarding → Vacuum freeze-drying → Shatter → Blend → Detection → Packaging → Finished Product ↑ ↑ Acceptance Acceptance ↑ ↑ Excipients Inner packaging bag
💡 Enzyme Activity Definition: Nattokinase reacts with fibrin to hydrolyze the peptide bonds of fibrin. The hydrolysis reaction changes the absorbance of the solution at 275 nm of ultraviolet light. One activity unit (1 FU) refers to the energy consumed for every 0.01 increase in the absorbance value at 275 nm.
Certificate of Analysis
Item Specification Result Test Method
Appearance Fine Powder Conforms NLS-QCS-1008
Color Yellow white – off white Conforms GB/T 5492-2008
Odor Characteristic Conforms GB/T 5492-2008
Taste Characteristic Conforms GB/T 5492-2008
Part Used Seeds Conforms /
Drying Method Freeze drying Conforms /
Physical Characteristics
Particle Size (80 mesh) NLT 95% through 80 mesh Conform GB/T 5507-2008
Moisture <5.0% 3.8% GB/T 14769-1993
Ash Content <5.0% 2.6% AOAC 942.05, 18th
Solvent Residue Eur Pharm Conform NLS-QCS-1007
Heavy Metals
Total Heavy Metals <10 ppm Conform USP <231>, method II
As <2.0 ppm Conform AOAC 986.15, 18th
Pb <2.0 ppm Conform AOAC 986.15, 18th
Cd <0.5 ppm Conform AOAC 986.15, 18th
Hg <0.5 ppm Conform AOAC 971.21, 18th
Pesticide Residue
666 <0.2 ppm Conform GB/T 5009.19-1996
DDT <0.2 ppm Conform GB/T 5009.19-1996
Microbiological Tests
Total Plate Count <1,000 cfu/g Conform AOAC 990.12, 18th
Total Yeast & Mold <100 cfu/g Conform FDA (BAM) Chapter 18, 8th Ed.
E. Coli Negative Negative AOAC 997.11, 18th
Salmonella Negative Negative FDA (BAM) Chapter 5, 8th Ed.
Effects of Different Factors on Enzyme Activity
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Functions & Applications
  • ❤️
    Nattokinase helps dissolve blood clots and lower blood lipids, making it highly effective in protecting against and supporting cardiovascular and cerebrovascular health.
  • ⚖️
    It supports healthy hormone balance, aids detoxification, improves skin appearance, and assists with weight and fat management.
  • 🛡️
    It also offers antioxidant and anti-fatigue benefits, helping to slow down the aging process.
  • 💊
    Absorbed easily through the intestines, it boosts thrombolytic activity in the body, reduces the risk of heart attack, and supports stronger heart function.
Application of Nattokinase
Application of Nattokinase 1
Storage

🌡️ Keep in a cool, dry and dark place. Storage temperature: below 0°C.

⚠️ Prolonged or improper storage may reduce enzyme activity. If exposed to high temperature or humidity, an appropriate increase in dosage is recommended.

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Packing
Weight Packing Method
1 kg Bag/kg, box outside (double plastic bag + aluminum foil bag inside)
10 kgs, 25 kg or more By drums or carton (2 layers plastic bag inside)
packaging
Delivery
Weight Delivery Method Delivery Time Destination
1 kg – 25 kgs EMS, DHL, UPS, FedEx 3–7 days Door to door
25 kgs – 100 kgs DHL, FedEx, by Air 3–7 days Door to door (to Airport by Air)
More than 100 kgs By Air 3–7 days Door to Airport
By Sea 10–35 days Door to port
Logistics
Logistics
Frequently Asked Questions (FAQ)
Q
What is Nattokinase and where does it come from?
A
Nattokinase (NK) is a serine protease naturally derived from Bacillus subtilis natto during the fermentation of soybeans into natto. It is known for its potent thrombolytic properties and cardiovascular benefits.
Q
What is the enzyme activity level of your Nattokinase product?
A
Our Nattokinase is produced via liquid fermentation and nanobiotechnology, achieving a kinase activity exceeding 50,000 Fu/g, ensuring high potency and consistent quality.
Q
What are the optimal storage conditions for Nattokinase?
A
Nattokinase should be stored in a cool, dry, and dark environment at temperatures below 0°C. Exposure to high temperatures or extreme pH conditions will cause denaturation and loss of enzyme activity.
Q
What packaging options are available for bulk orders?
A
For 1 kg orders, the product is packed in a bag/kg with a double plastic bag and aluminum foil bag inside a box. For 10 kg, 25 kg or larger quantities, drums or cartons with 2 layers of plastic bag inside are used.
Q
How long does delivery take and what shipping methods are available?
A
For shipments up to 100 kgs, delivery via EMS, DHL, UPS, or FedEx typically takes 3–7 business days door-to-door. For orders over 100 kgs, air freight or sea freight options are available.
Q
What quality certifications and testing standards does your Nattokinase meet?
A
Our Nattokinase undergoes comprehensive testing including physical characteristics, heavy metals, pesticide residues, and microbiological tests. All results conform to international quality standards with no detectable pathogens.

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