Premium bioactive ingredients & dietary raw materials formulated to global pharmacological and food-grade standards.
Bifidobacterium longum subsp. longum is one of the most prominent taxonomical representatives of the human microbiome. As an anaerobic, Gram-positive, non-spore-forming rod-shaped bacterium, it represents an essential physiological barrier colonizing the human gastrointestinal tract from infancy through senescence. From a biotechnology perspective, the production of clinically effective and highly stable B. longum susp. longum requires extreme environmental control during fermentation, cryogenic freezing, and microencapsulation.
Many low-cost probiotics available on the open market suffer from premature viability decay because their formulations do not safeguard against cellular oxidation and osmotic pressure. Shaanxi ShineHerb Biotech Co., Ltd. offers customized physiological stabilizing technologies that protect cell wall integrity through patented lyophilization processes. This ensures active colony forming units (CFU) remain highly stable throughout shelf-life, outperforming standard generic fermentations by up to 240% under ambient testing environments.
How advanced bio-engineering is transforming the stability, bio-availability, and therapeutic efficacy of commercial probiotic strains.
To overcome the harsh environment of gastric acid (pH 1.5 - 2.0) and high concentrations of bile salts, we utilize an advanced multi-layered lipid microencapsulation process. This ensures maximum survival during gastric transit, releasing live bacteria directly into the target intestine.
Bifidobacterium longum is inherently strictly anaerobic. Our innovative breeding and fermentation protocols employ progressive oxygen acclimation combined with nitrogen protective packaging, guaranteeing robust stability under aerobic packaging conditions.
Synthesizing B. longum susp. longum with targeted prebiotics (such as Galactooligosaccharides and Fructooligosaccharides) ensures immediate colonization upon delivery. We supply customized synergistic premixes formulated to customer specification profiles.
Enabling pharmaceutical, food and health supplement sectors with versatile therapeutic applications.
By reinforcing tight junctions (proteins ZO-1 and Occludin) and secreting short-chain fatty acids (SCFAs), our therapeutic strains inhibit competitive pathogens such as E. coli and Salmonella, supporting normal gut motility and nutrient absorption.
Clinically shown to stimulate the production of anti-inflammatory cytokines like Interleukin-10 (IL-10) while moderating pro-inflammatory markers, providing targeted relief for conditions like Irritable Bowel Syndrome (IBS) and chronic systemic inflammation.
Emerging medical research links *Bifidobacterium longum* to neuroactive compound pathways. Through direct interaction via the vagus nerve and systemic immune modulation, it assists in manufacturing essential neurotransmitters, improving cognitive vitality.
At Shaanxi ShineHerb Biotech Co., Ltd., we combine traditional fermentation heritage with smart-factory automation (Industry 4.0 principles). Based in the Hi-Tech Zone of Xi'an, Shaanxi Province, our manufacturing plants represent the highest standards of structural integrity and automation.
Established in 2002, Shaanxi ShineHerb Biotech Co., Ltd. is a leading high-tech enterprise specializing in the extraction of premium ingredients, development of advanced enzyme formulations, custom probiotic cultures, and clinical-grade health compound solutions. We serve demanding markets across 50+ countries.
Our QC framework spans raw material isolation, advanced high-performance liquid chromatography (HPLC) tests, gas chromatography (GC), and heavy metal validation checks conforming to USP, EP, and CP guidelines.
Whether you require deep bulk powder, tablets, or custom softgel or gummy contracts (OEM/ODM support), our state-of-the-art facilities deliver. We provide swift custom formulation, flavor configuration, and tailored label design under rigid regulatory supervision.
Quality and safety compliance represents the cornerstone of our company's corporate identity. ShineHerb Biotech maintains a robust compliance framework certified by world-leading safety institutions.
Global Standard Recognition
US Regulatory Compliance
Third-Party Quality Verification
Pure & Clean Ingredients
Critical Point Risk Controlled
Rigid Production Standards
High-Quality Jewish Dietary
Bring your custom formulation dreams to commercial execution with our dedicated OEM & ODM support. From fine raw functional powders to convenient tablets, from easy-to-swallow capsules (hard and soft) to pleasant, highly absorbable gummies and solid beverage stick packs.
Global distribution of live microbes requires experienced, dynamic shipping protocols. At ShineHerb Biotech, we ensure zero shipping worries with our resilient, temperature-controlled, multi-channel shipping network.
Optimized bulk logistics routes keeping expenses clean.
Courier integrations including DHL, FedEx, UPS & EMS.
DDP and DDU operations handling customs and duties.
Critical commercial and scientific inquiries resolved by ShineHerb's Chief Scientific Officer.
Expand your formulations with our certified active compounds, functional nutrients, and enzymes.