Shikimic Acid, commonly recognized as 3,4,5-trihydroxy-1-cyclohexene-1-carboxylic acid, stands as a critical biochemical hub. It functions as a key precursor in the shikimate pathway—a metabolic route essential for biosynthesis of aromatic amino acids (phenylalanine, tyrosine, and tryptophan) in plants, fungi, and bacteria. The commercial importance of bulk Shikimic Acid peaked internationally due to its critical role as the structural building block for Oseltamivir Phosphate (commonly sold under the trade name Tamiflu®), a key frontline neuraminidase inhibitor used to combat global influenza outbreaks including H5N1, H1N1, and seasonal epidemics.
Historically, the extraction of high-purity Shikimic Acid relied almost exclusively on the harvesting of Chinese Star Anise (Illicium verum Hook. f.). This method presented massive supply chain vulnerabilities due to the highly seasonal crop cycles, geographical concentration, and vulnerability of star anise yields to weather patterns. Modern industry developments have seen the introduction of advanced biosynthetic approaches using genetically engineered Escherichia coli strains to perform microbial bioconversion of glucose. However, high-quality, natural star anise extraction remains the premium standard for clean-label, bio-based cosmetics, organic food preservation, and specialized pharmaceutical formulations globally.
Today, the chemical and cosmetic industries are witnessing a surge in localized demand for Shikimic Acid due to its unique physiological properties. Its multifunctional structure—bearing three hydroxyl groups and a carboxylic acid moiety—allows it to serve as a versatile chiral building block in green chemistry and organic synthesis, paving the way for next-generation antimicrobial agents, safe plasticizers, and high-performance dermatological compounds.
Serves as the vital chiral base material required to synthesize Oseltamivir, keeping global antiviral stockpile networks supplied during seasonal pathogen threats.
Regarded as a highly effective, non-irritating alternative to alpha-hydroxy acids (AHAs) and beta-hydroxy acids (BHAs) for dermal cell regeneration and acne control.
Purchasing agents and formulation scientists seeking industrial-grade bulk supply of Shikimic Acid require precise compliance metrics. Shaanxi ShineHerb Biotech Co., Ltd. supplies premium-grade Shikimic Acid sourced through multi-stage crystallization and chromatography, ensuring structural integrity and compatibility in sensitive chemical reactions. Below are the key scientific parameters of our pharmaceutical and cosmetic grade bulk powders:
Specification: ≥ 98.0% to 99.5% Pure Powder (Crystalline)
Validated through high-performance liquid chromatography using photodiode array detection (HPLC-DAD) under strict GLP protocols to ensure complete batch consistency.
Melting Point: 185°C - 191°C
Specific Rotation: [α]D20 = -180° to -184°
Solubility: Completely soluble in water, ethanol, and methanol; insoluble in chloroform.
Loss on Drying: ≤ 1.0%
Heavy Metals: ≤ 10 ppm (As ≤ 1ppm, Pb ≤ 1ppm)
Pesticide Residues: Fully compliant with European Pharmacopoeia (EP 2.8.13) limits.
Welcome to Shaanxi ShineHerb Biotech Co., Ltd. — Your Scientific Partner in Pure Phytochemicals and Enzymes.
Shaanxi ShineHerb Biotech Co., Ltd. is a professional enterprise engaged in the research, production, and exports of Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates. We are committed to providing global customers with competitive pricing, stable and reliable product quality, and professional, efficient services.
With over 20 years of experience in the raw materials industry, ShineHerb Biotech continues to strengthen its technical capabilities and improve product quality. Our main products include Lactase, Bromelain, Pancreatin, Papain, Quercetin, N-Acetyl-L-Cysteine (NAC), PQQ, and Glucosamine Sulfate 2KCL, among others. These ingredients are widely used in pharmaceuticals, dietary supplements, beverages, cosmetics, and food additives.
At present, our products are exported to more than 50 countries and regions, including Europe, North America, and Southeast Asia, and have gained wide recognition and trust from customers worldwide.
Used widely in high-end European and North American skincare lines as a structural alternative to harsh synthetic peeling agents. Excellent for gentle exfoliating serums, acne patch formulation, skin-lightening products, and anti-pollution creams. Its natural extraction makes it ideal for Eco-cert and Clean Beauty brands targeting botanical-based peeling claims.
A global pharmaceutical standard starting material. Major APIs for antiviral therapeutics utilize the chiral carbon backbone of Shikimic Acid, which significantly reduces the synthetic steps required to build complex rings like oseltamivir phosphate. Vital for contract manufacturing organizations (CMOs) specialized in pharmaceutical intermediate synthesis.
Functions as a natural antioxidant and shelf-life extender in meat packaging and beverage processing. Also acts as an intermediate for non-toxic herbicides and agricultural growth regulators, promoting bio-compatible farming practices in regions seeking alternatives to synthetic glyphosates.
Geographical Synergy: Over 80% of the world’s natural star anise fields are located in southwest China (Guangxi and Shaanxi provinces). Our manufacturing plants are strategically situated to gain direct, uninterrupted access to raw materials, eliminating international logistics bottlenecks and ensuring stable raw material costs.
Green Extraction & Energy Innovation: Traditionally, organic solvents like dichloromethane were used in the extraction of raw materials, raising health and environmental concerns. Shaanxi ShineHerb Biotech implements modern, closed-loop aqueous and ethanol extraction technology combined with continuous countercurrent extraction processes. This not only improves yield output by up to 25% but also guarantees a clean, solvent-residue-free powder compliant with FDA, EU, and EPA regulations.
Automated Production Scale: Our manufacturing plant operates 24/7 automated pipelines, integrating advanced membrane filtration, low-temperature vacuum concentration, and high-efficiency spray drying. This combination prevents thermal degradation of active compounds, maintaining structural purity and preventing coloration changes in final products.
Our quality management systems are constructed strictly under USP, EP, FCC, and CP standards. We utilize multi-point validation from raw plant sorting to cleanroom packaging, preventing cross-contamination.
Since our inception, we have built robust international supply partnerships. We understand the specific regulatory frameworks governing entry of ingredients into the USA, EU, Asia-Pacific, and South American markets.
We supply bulk powder in multiple physical grades (micronized powders for direct tableting, crystal granules for dissolution, and customized liquid preparations) to fit any client's technical setup.
Risk Controlled Food Safety
Rigid Production Standards
Kosher Certified Raw Materials
ISO9001 Management Systems
US FDA Registered Facility
Rigorous Third-Party Audited
Pure & Halal Compliant
To help clients accelerate product launches, ShineHerb Biotech offers complete, turn-key manufacturing capabilities. We process high-purity natural extracts into the most appropriate dosage forms:
Our packaging facilities support private labeling, custom sachet fillings, blister pack layouts, and container packaging according to specifications compliant with local FDA and EU retail requirements.
Ensuring timely delivery of sensitive chemical intermediates is core to our service. We structure custom supply chain packages designed to lower shipping risks and minimize customs delays:
Natural Shikimic Acid is extracted from the seed pods of Chinese Star Anise (Illicium verum) using polar extraction solvents and refining chromatography. It is highly valued in the premium cosmetic sector due to natural certification standards (such as Cosmos/Ecocert) and clean-label cosmetic formulations. Synthetic or biosynthetic Shikimic Acid is produced through microbial fermentation of glucose using metabolically engineered strains of Escherichia coli or Saccharomyces cerevisiae. While biosynthetic versions offer high batch-to-batch consistency and a decouple from weather-driven star anise harvests, natural star anise extract remains the dominant choice for traditional herbal-based wellness formulations and eco-friendly consumer goods.
In dermatology, Shikimic Acid is considered a highly effective, non-irritating alternative to classic alpha-hydroxy acids (AHAs) and salicylic acid (BHA). It exhibits strong peeling action without causing significant erythema (redness) or skin barrier irritation. Additionally, Shikimic Acid acts as a natural inhibitor of 5-lipoxygenase, which helps control sebum production and reduces acne formation. Its antioxidant properties help neutralize free radicals generated by UV exposure, preventing structural collagen breakdown and providing clear anti-aging benefits when integrated into serums at 1% to 3% concentration levels.
Every single batch of our bulk Shikimic Acid undergoes strict analytical screening before leaving our facility. We utilize Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to monitor heavy metals (maintaining levels below 10ppm overall, with Lead and Arsenic at less than 1ppm). For pesticide residues, our batches are tested using Gas Chromatography-Mass Spectrometry (GC-MS) to ensure complete alignment with the strict regulations of the European Pharmacopoeia (EP 2.8.13) and United States Pharmacopeia (USP) guidelines. A comprehensive Certificate of Analysis (COA) detailing these findings is provided with every shipment.
Our bulk Shikimic Acid has a validated shelf life of 24 months from the manufacturing date, provided it remains in its original, unopened packaging. To preserve its high chemical purity and prevent moisture absorption or oxidation, the powder must be stored in a cool, dry warehouse environment, away from direct sunlight, heat, and moisture. The inner packaging consists of double-layered food-grade polyethylene bags, housed within a durable fiber drum.
Yes, we offer custom processing to meet your manufacturing requirements. Our standard crystalline powder can be micronized to achieve particle size distributions of 80 mesh, 100 mesh, or finer, utilizing specialized air-jet milling technology. This is particularly beneficial for manufacturers formulating solid dosage capsules or direct-compression tablets, as it enhances blend uniformity, dissolution kinetics, and bioavailability in the final product.
For standard in-stock batches of Shikimic Acid, we initiate packaging and dispatch within 3 to 7 working days. Large contract orders or customized manufacturing runs generally require a production lead time of 2 to 4 weeks. We support flexible payment options for established partners, including Telegraphic Transfer (T/T), Letter of Credit (L/C) at sight, and standard credit terms for long-term clients, alongside DDP/DDU shipping modes to minimize logistics friction.
Looking ahead, ShineHerb Biotech will continue to adhere to quality as the foundation and customer needs as the driving force, continuously improving product quality and service standards. We place great importance on building long-term and stable partnerships with our customers, and are committed to providing global clients with reliable product quality and professional services.
Whether you require a trial batch of high-purity Shikimic Acid for pilot testing, or a regular multi-ton container supply contract, our laboratory and export division are equipped to support you.
ShineHerb
