Discover our highly active compounds, enzymes, and natural ingredients engineered for regulatory compliance and optimal bioavailability.
Shaanxi ShineHerb Biotech Co., Ltd. is a leading global developer, manufacturer, and exporter of high-purity enzyme preparations, natural plant extracts, vitamins, amino acids, and active pharmaceutical intermediates. Situated in the Hi-Tech Zone of Xi'an, Shaanxi Province, our enterprise leverages advanced biosynthesis and traditional botanical extraction methods to supply high-end industries worldwide.
With over two decades of robust experience in the raw materials industry, we remain committed to technological innovation, rigorous GMP standard alignment, and strict analytical verification (USP, EP, CP). Our operations span more than 50 countries across North America, Europe, and Asia-Pacific, delivering unmatched batch-to-batch consistency and technical documentation.
A deep technical and commercial analysis of Sclareolide (CAS 564-20-5) in the modern formulation landscape.
Sclareolide is a natural sesquiterpene lactone derived primarily from the cultivation of Clary Sage (Salvia sclarea). Structurally relative to labdane diterpenoids, this compound is highly valued across multiple chemical sectors. In the fine fragrance industry, it is the primary precursor for the synthesis of Ambroxide (Ambrox), the principal organoleptic element of natural ambergris. As global maritime regulations and ethical standards phase out the sourcing of natural sperm whale ambergris, high-purity Sclareolide has transitioned from a niche substitute to an irreplaceable ecological benchmark.
Beyond olfactory applications, the physiological pathways of Sclareolide have stimulated immense demand within the cosmetic and weight management sectors. It acts as an intracellular cAMP (cyclic adenosine monophosphate) promoter, stimulating thermogenesis and lipolysis. In dermatology, its ability to down-regulate melanogenesis via MITF pathway inhibition has positioned it as a premium skin-brightening active. Today, Europe and North America control the majority of consumption shares, while manufacturing centers in Shaanxi, China, supply the bulk of the global market thanks to optimized crop integration and advanced crystallization processes.
| Parameter / Specification | Standard Limits | Analytical Method | Industrial Application |
|---|---|---|---|
| Appearance | Off-white to white crystalline powder | Visual Inspection | All formulations |
| Assay (Purity) | ≥ 98.0% | HPLC-ELSD / GC-MS | Fragrance synthesis & Cosmetics |
| Melting Point | 124.0°C to 127.0°C | Capillary Method | Stability indicator |
| Specific Optical Rotation | -21.0° to -25.0° | Polarimetry | Isomeric verification |
| Heavy Metals (Pb, As, Cd, Hg) | ≤ 10 ppm total | ICP-MS | Dietary supplements & Skincare |
| Solvent Residue (Ethanol) | ≤ 0.5% (5000 ppm) | Headspace GC | GMP Compliance |
The global market for Sclareolide is shaped by two major macro trends: the rise of clean beauty and the industrial integration of green chemistry.
Exploring Shaanxi ShineHerb Biotech's dual extraction and biosynthesis approaches.
Our traditional extraction uses sustainably sourced Salvia sclarea straw. We run multi-stage solid-liquid extractions using food-grade ethanol. The crude resin undergoes molecular distillation to isolate the volatile fractions, followed by crystallization at -10°C to achieve a minimum purity of 98%.
ShineHerb Biotech is investing in genetically engineered yeast strains (Saccharomyces cerevisiae) to synthesize Sclareolide from simple sugars. This biological pathway minimizes crop season dependency, improves yield predictability, and reduces water and solvent consumption.
Using counter-current chromatography and controlled crystallization, we remove trace impurities like sclareol and other resinous compounds. This yields an odorless, pure white crystalline powder that integrates seamlessly into fine fragrances without altering scent notes.
How target industries utilize our Sclareolide powder to formulate high-performance products.
Improves skin luminosity and addresses hyperpigmentation by down-regulating melanin production. It also acts as an anti-inflammatory agent, making it suitable for sensitive skin lines and sun-care recovery creams.
Acts as a chemical precursor for synthesizing Ambroxide, providing excellent scent fixation, diffusion, and heat stability in premium perfumes and soaps.
Stimulates lipolysis in adipocytes by activating adenylate cyclase. This boosts cyclic AMP (cAMP) levels, helping support thermogenesis and fat metabolism.
Acts as a natural defense elicitor against rusts, powdery mildew, and bacterial blights. It stimulates the plant's systemic acquired resistance (SAR) pathway, offering a non-toxic alternative to synthetic agricultural chemicals.
From raw crystalline powder to finished retail formulations, we support your brand growth.
Shaanxi ShineHerb Biotech offers comprehensive contract manufacturing and private label solutions. Utilizing our state-of-the-art facilities, we handle everything from formula development to final packaging.
We maintain strict quality benchmarks to ensure seamless market access globally.
Food Safety Management & Risk Controlled
Rigid Production Standards
Certified for Diverse Dietary Needs
International Industry Standards
Compliant U.S. FDA Ingredients
Rigorous Quality Control Verified
Clean & Pure Certified
Watch our facility operations and quality control processes firsthand.
To ensure timely delivery of sensitive materials, we provide customized supply chain solutions for our global partners.
Answers to common chemical, formulary, and logistical questions from our technical team.
Explore our diverse inventory of dietary, food, cosmetic, and pharmaceutical grade ingredients.
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