Explore our core bulk raw materials supplied to global pharmaceutical, nutraceutical, and cosmetic brands.
An Industrial Guide for Global Procurement and R&D Directors
Lacticaseibacillus rhamnosus (historically classified as Lactobacillus rhamnosus) is a Gram-positive, rod-shaped, facultatively anaerobic bacterium. Noted for its heterofermentative properties, it stands as one of the most widely researched probiotic species globally, with extensive clinical backing for human gastrointestinal and immunological applications.
Its structural robustness, derived from a thick peptidoglycan layer and adhesive pili (specifically SpaCBA pili), allows it to survive the high acidity of the stomach and successfully colonize the intestinal mucosa. This makes it an ideal strain for nutritional supplements and clinical-grade formulations.
The global probiotic market is transitioning rapidly toward strain-specific solutions. Global buyers from North America, Europe, and the APAC regions require high-CFU (Colony Forming Unit) powders to fulfill diverse application standards. Lacticaseibacillus rhamnosus is widely utilized in pediatric drop formulations, adult immune-support capsules, and skin care microbiomes.
With a compound annual growth rate (CAGR) exceeding 8.3% in the probiotic ingredients segment, securing a reliable, high-yield manufacturing partner who can supply stable concentrations (up to 500 Billion CFU/g) is crucial for brand owners aiming to minimize overages during product shelf-life.
"Information Gain Advantage: Unlike standard lactic acid bacteria, Lacticaseibacillus rhamnosus maintains superior biological activity when paired with prebiotic fibers like FOS and Inulin. Our optimized cryoprotectant technology ensures a viability retention rate of over 92% after 24 months at standard room temperature."
At Shaanxi ShineHerb Biotech Co., Ltd., we combine over 20 years of botanical and biological manufacturing expertise to optimize probiotic yields. Our manufacturing processes in China utilize state-of-the-art automated bioreactors, operating under sterile conditions that prevent phage contamination.
Our China factory efficiency translates to robust economies of scale, allowing us to supply ultra-high activity powders at competitive price-points. Through optimized nitrogen feed controls and advanced multi-stage vacuum freeze-drying (lyophilization), we protect the cellular integrity of the bacteria, yielding a free-flowing, easily dispersible powder suitable for tableting and capsule-filling.
Strict monitoring of water activity (aw < 0.05) prevents cellular degradation.
Supplied in customized carrier options, including Maltodextrin, Starch, or Microcrystalline Cellulose.
Standard bulk parameters for Lacticaseibacillus Rhamnosus Powder
| Specification Parameter | Standard Target Value | Testing Methodology |
|---|---|---|
| Appearance | White to light-cream, free-flowing powder | Organoleptic assessment |
| Viable Cell Count (CFU/g) | 100 Billion / 200 Billion / 500 Billion CFU/g | Plate count agar method (ISO 27205) |
| Loss on Drying | ≤ 5.0% | 105°C, 2 hours |
| Water Activity (aw) | ≤ 0.05 | Hygrometer determination |
| Heavy Metals (as Pb) | ≤ 1.0 ppm | ICP-MS analysis |
| Coliforms | Negative (< 10 CFU/g) | FDA-BAM Chap 4 |
| Salmonella / S. aureus | Absent in 25g | AOAC Official Methods |
Welcome to learn about our company. Shaanxi ShineHerb Biotech Co., Ltd. is a professional enterprise engaged in the research, production, and exports of Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates. We are committed to providing global customers with competitive pricing, stable and reliable product quality, and professional, efficient services.
With over 20 years of experience in the raw materials industry, ShineHerb Biotech continues to strengthen its technical capabilities and improve product quality. Our main products include Lactase, Bromelain, Pancreatin, Papain, Quercetin, N-Acetyl-L-Cysteine (NAC), PQQ, and Glucosamine Sulfate 2KCL, among others. These ingredients are widely used in pharmaceuticals, dietary supplements, beverages, cosmetics, and food additives.
At present, our products are exported to more than 50 countries and regions, including Europe, North America, and Southeast Asia, and have gained wide recognition and trust from customers worldwide.
Why procurement professionals worldwide choose ShineHerb Biotech as their long-term supply partner.
Quality is the core of a company’s survival and development. ShineHerb Biotech has established a strict quality management system, covering raw material inspection, production process control, solvent and excipient management, and final product testing, ensuring rigorous quality control at every stage.
We provide extensive technical support for our client base, including stability study documentation, strain identification reports, and compatibility testing results for multi-strain formulations. Our scientists assist in optimizing final formulations for maximum bio-efficacy.
Our manufacturing and packaging plants are fully compliant with Good Manufacturing Practice (GMP) standards. Comprehensive microbial monitoring, batch-to-batch tracking, and thorough sanitation routines guarantee pure, uncontaminated probiotic powders.
Powder, Tablets, Capsules, Gummies, Solid Beverages
From fine powders to convenient tablets, from easy-to-swallow hard capsules to highly absorbable softgels, and fun, nutritious gummies — ShineHerb Biotech offers full-format customized manufacturing. We assist you from initial formulations to final retail-ready product packaging.
Our global certifications guarantee that our materials meet strict regional compliance standards, ensuring seamless custom clearance and market access.
Guaranteed Food Safety Management • Risk Controlled
Good Manufacturing Practice • Rigid Production Standards
High-Quality Products with Kosher Certification for All Dietary Needs
Global Standard Recognition • Meet International Industry Requirements
U.S. Food & Drug Administration Compliance. Safe Ingredients for Global Markets
Rigorous Quality Control Verified by a Global Leader in Inspection
Suitable for Muslim Consumers • Pure & Clean. Expand Your Market Reach
A closer look at our high-tech equipment and extraction facility located in Xi'an Hi-Tech Zone.
Watch our corporate presentation video illustrating our scale, chemical testing equipment, and automated warehouse management.
We provide robust cargo monitoring from factory gate to final destination port. Ensuring cold-chain integrity or shipping under temperature-controlled environments is optional based on customer requests.
Detailed technical answers regarding bulk procurement and application protocols
Explore our selection of top-selling active ingredients exported to over 50 countries.
ShineHerb
