Premium raw materials and specialized extracts engineered to deliver optimal stability and purity for global health, wellness, and functional ingredient formulations.
Usnic acid (CAS No: 125-46-2 / 7562-61-0) is a unique dibenzofuran derivative naturally occurring in various lichen genera, predominantly in Usnea (such as Usnea barbata, Usnea longissima), Cladonia, and Parmelia. Structurally complex, it exists in two enantiomeric forms: d-usnic acid and l-usnic acid. The d-enantiomer is heavily prized for its potent antibacterial profile against Gram-positive pathobionts without disrupting physiological balance.
As a professional Usnic Acid manufacturer, Shaanxi ShineHerb Biotech Co., Ltd. utilizes eco-friendly extraction techniques, primarily focusing on supercritical CO2 extraction and premium food-grade recrystallization. This results in an ultra-pure, light-yellow crystalline powder with typical purities of ≥98% (HPLC), keeping residual solvents well below the strict thresholds outlined by the European Pharmacopoeia (EP) and United States Pharmacopeia (USP).
Analyzing key market forces driving the integration of Usnic Acid into clean-label cosmetics, functional therapeutics, and veterinary medicine.
Cosmetic formulators are actively replacing synthetic preservatives (like parabens and phenoxyethanol) with natural bacteriostatic agents. Usnic acid's selective action against acne-causative bacteria (Cutibacterium acnes) makes it a preferred choice for anti-acne skincare lines.
With mounting regulatory pressure to limit clinical antibiotics in livestock feed, veterinary formulators are using Usnic Acid as a natural feed additive. Its proven efficacy against Clostridium perfringens supports gut homeostasis in poultry and swine.
Global raw material sourcing mandates precise toxicological clearances. Sourcing from a certified manufacturer ensures that the supply conforms with REACH (EU) registries, INCI lists, and local cosmetic ingredient limits.
Founded in 2002, Shaanxi ShineHerb Biotech Co., Ltd. is a modern biotech enterprise located in the High-Tech Zone of Xi'an, Shaanxi Province. We specialize in the research, development, extraction, and global distribution of top-tier active pharmaceutical ingredients, botanical extracts, enzyme preparations, amino acids, and vitamins.
We manage a strict quality ecosystem following international protocols to ensure every batch of Usnic Acid, Lactase, Bromelain, and other specialty enzymes matches USP, EP, and CP guidelines. Our supply footprints cover 50+ countries across North America, Europe, and Asia-Pacific.
Comprehensive standard parameters of our premium Usnic Acid Powder, optimized for safety, stability, and formulation ease.
| Specification Parameters | Standard Protocol Limit (HPLC Range) | Testing Methodology Reference |
|---|---|---|
| Appearance | Light Yellow Crystalline Powder | Visual Inspection |
| Active Assay (Purity) | ≥98.0% (d-Usnic Acid / l-Usnic Acid) | HPLC Method |
| Melting Point | 201°C - 204°C | USP <741> Crystalline Melting Range |
| Loss on Drying | ≤0.5% | 105°C, 3 Hours, USP <731> |
| Heavy Metals (Pb, Cd, As, Hg) | <10 ppm (Individual components <1 ppm) | ICP-MS Method |
| Residual Solvents | Ethanol <5000 ppm, Methanol (Absent/ND) | GC-FID (USP <467> Class 2/3) |
| Microbiological Bioburden | TAMC <1000 cfu/g, TYMC <100 cfu/g, Pathogens (Absent) | USP <61> & <62> |
How we address typical formulation challenges of Usnic Acid such as low water solubility and thermal degradation.
Usnic acid is hydrophobic and poorly soluble in water. We offer micro-particle size customization (down to D90 < 10 microns) and advise clients on cyclodextrin complexation and liposomal encapsulation to improve bio-availability.
We provide multiple industrial packaging sizes tailored to your manufacturing lines: from 1kg aluminum foil bags to 25kg fiber drums, with double-layer PE liners protecting the raw materials from moisture and oxidation.
Our expert R&D team assists cosmetics and pharmaceutical developers with raw material compatibility profiles, pH stability profiles (stable between pH 4.5 - 7.0), and co-preservation synergy studies.
Our commitment to green chemistry, raw material tracking, and scaling up lichen-derived compounds efficiently.
We partner with local harvesters in unpolluted mountainous zones to source wild-crafted, sustainable Usnea barbata lichens, ensuring zero environmental depletion.
Using high-pressure CO2 fluids to extract the organic active fractions, avoiding chlorinated solvents and conserving the thermal stability of the usnic molecules.
Executing systematic crystallization phases using food-grade ethanol solvents to elevate final purities beyond 98.5% with minimum degradation.
Every single batch undergoes rigorous HPLC analysis, microbiological assays, and particle sizing before obtaining standard COA releases.
At Shaanxi ShineHerb Biotech Co., Ltd., we manage multi-channel shipping to deliver seamlessly across international boundaries. We support various modes of transport including:
Our factory processes and facilities are fully certified and verified to align with GMP, ISO9001, FDA, SGS, Kosher, Halal, and HACCP regulatory frameworks, providing comprehensive documentation packages (COA, MSDS, Allergen Statements, GMO-free Statements) for quick border clearing.
Access quick, direct technical answers regarding chemistry, stability, regulatory approvals, and purchasing terms.
Our raw materials conform to global quality protocols, backed by certified compliance audits.
Beyond bulk raw powder supply, Shaanxi ShineHerb Biotech Co., Ltd. provides comprehensive customized contract manufacturing and private label solutions. We transform active raw ingredients into market-ready formulations:
An inside look at our standardized processing operations, ensuring high product purity and batch-to-batch consistency.
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