High-purity raw materials sourced and processed under strict international pharmacopeia standards.
CAS 138-59-0, chemically recognized as Shikimic Acid ((3R,4S,5R)-3,4,5-trihydroxycyclohex-1-ene-1-carboxylic acid), is a vital organic compound occurring naturally in a variety of plants. Historically discovered in the Japanese flower *Illicium anisatum* (shikimi), it serves as a crucial metabolic intermediate in the shikimate pathway of plants, bacteria, and fungi.
From an industrial perspective, Shikimic Acid is the gold-standard starting material (chiral precursor) for the multi-step synthesis of Oseltamivir Phosphate (commercially known as Tamiflu), the leading antiviral medication used to treat and prevent Influenza A and Influenza B. Its structural configuration, containing three chiral centers in a cyclohexane ring, makes chemical synthesis from scratch economically unviable, elevating the importance of choosing reliable, high-capacity suppliers in China.
Our research and production models have adapted to meet the stringent demands of global biopharma, shifting from simple agricultural extraction to advanced hybrid production frameworks that guarantee consistent batch quality regardless of harvest seasonality.
Analyzing why the demand for CAS 138-59-0 continues to rise across pharmaceuticals, cosmetics, and nutraceuticals.
Governments and healthcare agencies globally maintain strategic national stockpiles of antiviral drugs. As global threats of avian flu (H5N1, H7N9) and seasonal influenza variations persist, the demand for Shikimic Acid as a raw API precursor remains high and inelastic.
Beyond influenza treatment, Shikimic Acid has emerged as a premium exfoliant in functional cosmetics. Acting as a gentle alternative to glycolic and salicylic acids, it displays excellent anti-acne, antimicrobial, and peeling properties without causing skin irritation, driving consumption in East Asia and Europe.
Emerging nutritional science indicates that derivatives of the shikimate pathway exhibit potential anti-inflammatory and antithrombotic activities. Health supplement companies are actively integrating standardized plant extracts rich in Shikimic Acid to target vascular health.
Your Reliable Manufacturer in Hi-Tech Zone Xi'an, Shaanxi Province
Established in 2002, Shaanxi ShineHerb Biotech Co., Ltd. has developed into a premier high-tech enterprise dedicated to the extraction, purification, synthesis, and export of Enzyme preparations, Natural plant extracts, Vitamins, Amino acids, and Pharmaceutical intermediates.
With an established base in the industrial heartland of Shaanxi Province, we optimize raw material sourcing from native regions while executing advanced crystallization and quality control protocols in our state-of-the-art facilities. Over two decades of experience translates into unparalleled supply chain security, regulatory expertise, and client-centric customized formulation support.
How ShineHerb Biotech combines advanced manufacturing technologies with geographical advantages to guarantee delivery.
The traditional extraction of Shikimic Acid heavily relied on harvesting the seed pods of *Illicium verum* (Chinese Star Anise). However, botanical sourcing is highly susceptible to climate shifts, typhoons, and seasonal harvest cycles, causing historical price volatility. To mitigate these risks, ShineHerb Biotech has adopted Factory 4.0 industrial principles.
Our integrated manufacturing approach balances direct-from-plantation botanical extraction with advanced microbial fermentation (biocatalysis). Utilizing engineered metabolic pathways in bacterial strains (such as modified *Escherichia coli*), we can biosynthesize CAS 138-59-0 from simple carbon sources like glucose. This hybrid model guarantees:
Our industrial-scale fermentation bioreactors operate 365 days a year, unaffected by agricultural bottlenecks or bad weather in harvesting seasons.
Biocatalytic synthesis reduces organic solvent consumption by up to 60%, drastically decreasing the carbon footprint and matching strict EU environmental regulations.
Automated control systems monitor pH, oxygen levels, and temperature, ensuring that every batch exhibits matching chromatographic and physical parameters.
Typical analytical parameters for ShineHerb Biotech CAS 138-59-0 (Shikimic Acid)
| Analysis Items | Specifications | Testing Methods |
|---|---|---|
| Appearance | White or almost white crystalline powder | Visual Inspection |
| Assay (HPLC) | ≥ 98.0% (Pharma & Cosmetic Grades available up to 99.5%) | HPLC-UV (Internal Standard) |
| Melting Range | 185.0 °C ~ 187.0 °C | Capillary Tube Method |
| Loss on Drying | ≤ 1.0% | 105°C, Constant Weight |
| Specific Rotation | -175° to -183° | Polarimeter |
| Heavy Metals | ≤ 10 ppm | Atomic Absorption (AAS) |
| Arsenic (As) | ≤ 2.0 ppm | ICP-MS |
| Total Plate Count | ≤ 1000 cfu/g | Microbiological culture |
Meeting requirements across regulatory authorities in North America, Europe, and Asia-Pacific.
Good Manufacturing Practice · Rigid Standards
U.S. FDA Registered Facility
Global Standard for Quality Management
Guaranteed Hazard Analysis Control
Dietary Compliance Approved
Islamic Dietary Standard Certified
Third-Party Testing & Verification
One-Stop Customized Solutions: Powder, Tablets, Capsules, Gummies & Solid Beverages
Understanding that different buyers require varying functional formulations, Shaanxi ShineHerb Biotech offers complete, state-of-the-art OEM & ODM solutions. Our contract manufacturing services turn raw ingredients into market-ready formulations tailored to your exact market positioning.
From custom particle sizes and micronization of Shikimic Acid to blending with synergistic compounds (such as Vitamin E, Quercetin, or Phytosterols), we handle formulation, pilot trials, packaging design, and heavy metal validation so you can concentrate exclusively on market growth.
Multiple shipping configurations to guarantee zero degradation of delicate chemical precursors.
Shikimic acid and associated pharmaceutical precursors must be kept dry and cool to maintain stable assay values. Our warehouse structures implement controlled relative humidity and temperature systems to prevent moisture absorption and enzymatic degradation during storage.
We provide multiple shipping strategies depending on order volume, lead times, and import regulations:
Take a virtual tour of our extraction facilities, research laboratories, and raw material processing workflows.
Essential insights for procurement managers and product formulators sourcing CAS 138-59-0.
Explore our high-demand active ingredients supplied to leading dietary supplement and cosmetics brands.
ShineHerb